Parsons R - Search Results

1

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.

Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. Li J, et al. Among authors: parsons r. Science. 1997 Mar 28;275(5308):1943-7. doi: 10.1126/science.275.5308.1943. Science. 1997. PMID: 9072974

2

Somatic mutations of PTEN in glioblastoma multiforme.

Wang SI, Puc J, Li J, Bruce JN, Cairns P, Sidransky D, Parsons R. Wang SI, et al. Among authors: parsons r. Cancer Res. 1997 Oct 1;57(19):4183-6. Cancer Res. 1997. PMID: 9331071

3

Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas.

Wang SI, Parsons R, Ittmann M. Wang SI, et al. Among authors: parsons r. Clin Cancer Res. 1998 Mar;4(3):811-5. Clin Cancer Res. 1998. PMID: 9533551

4

Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas.

Bose S, Wang SI, Terry MB, Hibshoosh H, Parsons R. Bose S, et al. Among authors: parsons r. Oncogene. 1998 Jul 9;17(1):123-7. doi: 10.1038/sj.onc.1201940. Oncogene. 1998. PMID: 9671321

5

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.

Li J, Simpson L, Takahashi M, Miliaresis C, Myers MP, Tonks N, Parsons R. Li J, et al. Among authors: parsons r. Cancer Res. 1998 Dec 15;58(24):5667-72. Cancer Res. 1998. PMID: 9865719

6

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome.

Liaw D, Marsh DJ, Li J, Dahia PL, Wang SI, Zheng Z, Bose S, Call KM, Tsou HC, Peacocke M, Eng C, Parsons R. Liaw D, et al. Among authors: parsons r. Nat Genet. 1997 May;16(1):64-7. doi: 10.1038/ng0597-64. Nat Genet. 1997. PMID: 9140396

7

Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a.

Fine B, Hodakoski C, Koujak S, Su T, Saal LH, Maurer M, Hopkins B, Keniry M, Sulis ML, Mense S, Hibshoosh H, Parsons R. Fine B, et al. Among authors: parsons r. Science. 2009 Sep 4;325(5945):1261-5. doi: 10.1126/science.1173569. Science. 2009. PMID: 19729658 Free PMC article.

8

A secreted PTEN phosphatase that enters cells to alter signaling and survival.

Hopkins BD, Fine B, Steinbach N, Dendy M, Rapp Z, Shaw J, Pappas K, Yu JS, Hodakoski C, Mense S, Klein J, Pegno S, Sulis ML, Goldstein H, Amendolara B, Lei L, Maurer M, Bruce J, Canoll P, Hibshoosh H, Parsons R. Hopkins BD, et al. Among authors: parsons r. Science. 2013 Jul 26;341(6144):399-402. doi: 10.1126/science.1234907. Epub 2013 Jun 6. Science. 2013. PMID: 23744781 Free PMC article.

9

Reduced expression of PTEN correlates with breast cancer progression.

Bose S, Crane A, Hibshoosh H, Mansukhani M, Sandweis L, Parsons R. Bose S, et al. Among authors: parsons r. Hum Pathol. 2002 Apr;33(4):405-9. doi: 10.1053/hupa.2002.124721. Hum Pathol. 2002. PMID: 12055674

10

PTEN loss inhibits CHK1 to cause double stranded-DNA breaks in cells.

Puc J, Parsons R. Puc J, et al. Among authors: parsons r. Cell Cycle. 2005 Jul;4(7):927-9. doi: 10.4161/cc.4.7.1795. Epub 2005 Jul 3. Cell Cycle. 2005. PMID: 15970699

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