Kane JM - Search Results

1

Preclinical characterization of MDL 27,192 as a potential broad spectrum anticonvulsant agent with neuroprotective properties.

Kehne JH, Kane JM, Chaney SF, Hurst G, McCloskey TC, Petty MA, Senyah Y, Wolf HH, Zobrist R, White HS. Kehne JH, et al. Among authors: kane jm. Epilepsy Res. 1997 Apr;27(1):41-54. doi: 10.1016/s0920-1211(96)01020-0. Epilepsy Res. 1997. PMID: 9169290

2

MDL 27,531 selectively reverses strychnine-induced seizures in mice.

Kehne JH, Kane JM, Miller FP, Ketteler HJ, Braun DL, Senyah Y, Chaney SF, Abdallah A, Dudley MW, Ogden AM, et al. Kehne JH, et al. Among authors: kane jm. Br J Pharmacol. 1992 Aug;106(4):910-6. doi: 10.1111/j.1476-5381.1992.tb14434.x. Br J Pharmacol. 1992. PMID: 1327393 Free PMC article.

3

MDL 26,479: a potential cognition enhancer with benzodiazepine inverse agonist-like properties.

Miller JA, Dudley MW, Kehne JH, Sorensen SM, Kane JM. Miller JA, et al. Among authors: kane jm. Br J Pharmacol. 1992 Sep;107(1):78-86. doi: 10.1111/j.1476-5381.1992.tb14466.x. Br J Pharmacol. 1992. PMID: 1330168 Free PMC article.

4

MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord.

Kehne JH, Ketteler HJ, Kane JM, McCloskey TC, Senyah Y, Palfreyman MG. Kehne JH, et al. Among authors: kane jm. Neurosci Lett. 1992 Nov 23;147(1):101-5. doi: 10.1016/0304-3940(92)90784-5. Neurosci Lett. 1992. PMID: 1480315

5

5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.

Kane JM, Staeger MA, Dalton CR, Miller FP, Dudley MW, Ogden AM, Kehne JH, Ketteler HJ, McCloskey TC, Senyah Y, et al. Kane JM, et al. J Med Chem. 1994 Jan 7;37(1):125-32. doi: 10.1021/jm00027a015. J Med Chem. 1994. PMID: 8289185

6

Synthesis and pharmacology of 3-aryl-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid derivatives.

Kane JM, Huber EW, Miller FP, Kehne JH. Kane JM, et al. Pharmazie. 1992 Apr;47(4):249-51. Pharmazie. 1992. PMID: 1518880

7

Enhancement of working memory performance in the rat by MDL 26,479, a novel compound with activity at the GABAA receptor complex.

Moran PM, Kane JM, Moser PC. Moran PM, et al. Among authors: kane jm. Brain Res. 1992 Jan 8;569(1):156-8. doi: 10.1016/0006-8993(92)90383-k. Brain Res. 1992. PMID: 1319259

8

2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.

Kane JM, Baron BM, Dudley MW, Sorensen SM, Staeger MA, Miller FP. Kane JM, et al. J Med Chem. 1990 Oct;33(10):2772-7. doi: 10.1021/jm00172a015. J Med Chem. 1990. PMID: 2170646

9

The enhancement of muscimol-stimulated 36C1 influx by the antispastic 5-aryl-3-(alkylsulfonyl)-4H-1,2,4-triazole (MDL 27,531) in rat brain membrane vesicles.

Miller JA, Braun D, Chmielewski PA, Kane JM. Miller JA, et al. Among authors: kane jm. Neurosci Lett. 1995 Dec 8;201(2):183-7. doi: 10.1016/0304-3940(95)12143-9. Neurosci Lett. 1995. PMID: 8848248

10

The effects of a potential antidepressant, 2,4-dimethyl-5-(3-fluorophenyl)-3H-1,2,4-triazole-3-thione, in an electrophysiological model responsive to desipramine.

Sorensen SM, Zwolshen JM, Kane JM. Sorensen SM, et al. Among authors: kane jm. Neuropharmacology. 1990 Jun;29(6):555-60. doi: 10.1016/0028-3908(90)90067-2. Neuropharmacology. 1990. PMID: 2385327

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