Oefner C - Search Results

1

Recombinant human renin produced in different expression systems: biochemical properties and 3D structure.

Mathews S, Döbeli H, Pruschy M, Bosser R, D'Arcy A, Oefner C, Zulauf M, Gentz R, Breu V, Matile H, Schlaeger J, Fischli W. Mathews S, et al. Among authors: oefner c. Protein Expr Purif. 1996 Feb;7(1):81-91. doi: 10.1006/prep.1996.0012. Protein Expr Purif. 1996. PMID: 9172787

2

Crystal structure of human dihydrofolate reductase complexed with folate.

Oefner C, D'Arcy A, Winkler FK. Oefner C, et al. Eur J Biochem. 1988 Jun 1;174(2):377-85. doi: 10.1111/j.1432-1033.1988.tb14108.x. Eur J Biochem. 1988. PMID: 3383852 Free article.

3

Renin inhibition by substituted piperidines: a novel paradigm for the inhibition of monomeric aspartic proteinases?

Oefner C, Binggeli A, Breu V, Bur D, Clozel JP, D'Arcy A, Dorn A, Fischli W, Grüninger F, Güller R, Hirth G, Märki H, Mathews S, M ller M, Ridley RG, Stadler H, Vieira E, Wilhelm M, Winkler F, Wostl W. Oefner C, et al. Chem Biol. 1999 Mar;6(3):127-31. doi: 10.1016/s1074-5521(99)89004-8. Chem Biol. 1999. PMID: 10074464

4

Substituted piperidines--highly potent renin inhibitors due to induced fit adaptation of the active site.

Vieira E, Binggeli A, Breu V, Bur D, Fischli W, Güller R, Hirth G, Märki HP, Müller M, Oefner C, Scalone M, Stadler H, Wilhelm M, Wostl W. Vieira E, et al. Among authors: oefner c. Bioorg Med Chem Lett. 1999 May 17;9(10):1397-402. doi: 10.1016/s0960-894x(99)00195-x. Bioorg Med Chem Lett. 1999. PMID: 10360744

5

Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon.

Oefner C, D'Arcy A, Hennig M, Winkler FK, Dale GE. Oefner C, et al. J Mol Biol. 2000 Feb 18;296(2):341-9. doi: 10.1006/jmbi.1999.3492. J Mol Biol. 2000. PMID: 10669592

6

Crystal structure of human platelet-derived growth factor BB.

Oefner C, D'Arcy A, Winkler FK, Eggimann B, Hosang M. Oefner C, et al. EMBO J. 1992 Nov;11(11):3921-6. doi: 10.1002/j.1460-2075.1992.tb05485.x. EMBO J. 1992. PMID: 1396586 Free PMC article.

7

Expression, purification and crystallization of fully active, glycosylated human interleukin-5.

Guisez Y, Oefner C, Winkler FK, Schlaeger EJ, Zulauf M, Van der Heyden J, Plaetinck G, Cornelis S, Tavernier J, Fiers W, et al. Guisez Y, et al. Among authors: oefner c. FEBS Lett. 1993 Sep 27;331(1-2):49-52. doi: 10.1016/0014-5793(93)80295-6. FEBS Lett. 1993. PMID: 8405410 Free article.

8

Piperidine-renin inhibitors compounds with improved physicochemical properties.

Güller R, Binggeli A, Breu V, Bur D, Fischli W, Hirth G, Jenny C, Kansy M, Montavon F, Müller M, Oefner C, Stadler H, Vieira E, Wilhelm M, Wostl W, Märki HP. Güller R, et al. Among authors: oefner c. Bioorg Med Chem Lett. 1999 May 17;9(10):1403-8. doi: 10.1016/s0960-894x(99)00196-1. Bioorg Med Chem Lett. 1999. PMID: 10360745

9

Structure and function of the dihydropteroate synthase from Staphylococcus aureus.

Hampele IC, D'Arcy A, Dale GE, Kostrewa D, Nielsen J, Oefner C, Page MG, Schönfeld HJ, Stüber D, Then RL. Hampele IC, et al. Among authors: oefner c. J Mol Biol. 1997 Apr 25;268(1):21-30. doi: 10.1006/jmbi.1997.0944. J Mol Biol. 1997. PMID: 9149138

10

The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae.

Hennig M, Dale GE, D'arcy A, Danel F, Fischer S, Gray CP, Jolidon S, Müller F, Page MG, Pattison P, Oefner C. Hennig M, et al. Among authors: oefner c. J Mol Biol. 1999 Mar 26;287(2):211-9. doi: 10.1006/jmbi.1999.2623. J Mol Biol. 1999. PMID: 10080886

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