Spaethe SM - Search Results

1

The regulation of CD11b integrin levels on human blood leukocytes and leukotriene B4-stimulated skin by a specific leukotriene B4 receptor antagonist (LY293111).

van Pelt JP, de Jong EM, van Erp PE, Mitchell MI, Marder P, Spaethe SM, van Hooijdonk CA, Kuijpers AL, van de Kerkhof PC. van Pelt JP, et al. Among authors: spaethe sm. Biochem Pharmacol. 1997 Apr 4;53(7):1005-12. doi: 10.1016/s0006-2952(96)00884-2. Biochem Pharmacol. 1997. PMID: 9174114 Free article. Clinical Trial.

2

Blockade of human neutrophil activation by 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]propoxy]phenoxy]benzoic acid (LY293111), a novel leukotriene B4 receptor antagonist.

Marder P, Sawyer JS, Froelich LL, Mann LL, Spaethe SM. Marder P, et al. Among authors: spaethe sm. Biochem Pharmacol. 1995 May 26;49(11):1683-90. doi: 10.1016/0006-2952(95)00078-e. Biochem Pharmacol. 1995. PMID: 7786309

3

Inhibition of ex vivo neutrophil activation by oral LY293111, a novel leukotriene B4 receptor antagonist.

Marder P, Spaethe SM, Froelich LL, Cerimele BJ, Petersen BH, Tanner T, Lucas RA. Marder P, et al. Among authors: spaethe sm. Br J Clin Pharmacol. 1996 Oct;42(4):457-64. doi: 10.1046/j.1365-2125.1996.43210.x. Br J Clin Pharmacol. 1996. PMID: 8904617 Free PMC article. Clinical Trial.

4

Flow cytometric evaluation of the effects of leukotriene B4 receptor antagonists (LY255283 and SC-41930) on calcium mobilization and integrin expression of activated human neutrophils.

Marder P, Schultz RM, Spaethe SM, Sofia MJ, Herron DK. Marder P, et al. Among authors: spaethe sm. Prostaglandins Leukot Essent Fatty Acids. 1992 Aug;46(4):265-70. doi: 10.1016/0952-3278(92)90033-f. Prostaglandins Leukot Essent Fatty Acids. 1992. PMID: 1329112

5

Effects of two leukotriene B4 (LTB4) receptor antagonists (LY255283 and SC-41930) on LTB4-induced human neutrophil adhesion and superoxide production.

Schultz RM, Marder P, Spaethe SM, Herron DK, Sofia MJ. Schultz RM, et al. Among authors: spaethe sm. Prostaglandins Leukot Essent Fatty Acids. 1991 Aug;43(4):267-71. doi: 10.1016/0952-3278(91)90041-3. Prostaglandins Leukot Essent Fatty Acids. 1991. PMID: 1658812

6

Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma.

Evans DJ, Barnes PJ, Spaethe SM, van Alstyne EL, Mitchell MI, O'Connor BJ. Evans DJ, et al. Among authors: spaethe sm. Thorax. 1996 Dec;51(12):1178-84. doi: 10.1136/thx.51.12.1178. Thorax. 1996. PMID: 8994512 Free PMC article. Clinical Trial.

7

The discovery of LY293111, a novel, potent and orally active leukotriene B4 receptor antagonist of the biphenylphenol class.

Sofia MJ, Floreancig P, Bach N, Baker SR, Nelson K, Sawyer JS, Baldwin R, Cockerham SL, Fleisch JH, Froelich LL, Jackson WT, Marder P, Roman CR, Saussy DL Jr, Silbaugh SA, Spaethe SM, Stengel PW. Sofia MJ, et al. Among authors: spaethe sm. Adv Exp Med Biol. 1997;400A:381-6. doi: 10.1007/978-1-4615-5325-0_51. Adv Exp Med Biol. 1997. PMID: 9547580 No abstract available.

8

Pharmacologic actions of the second-generation leukotriene B4 receptor antagonist LY293111: in vitro studies.

Jackson WT, Froelich LL, Boyd RJ, Schrementi JP, Saussy DL Jr, Schultz RM, Sawyer JS, Sofia MJ, Herron DK, Goodson T Jr, Snyder DW, Pechous PA, Spaethe SM, Roman CR, Fleisch JH. Jackson WT, et al. Among authors: spaethe sm. J Pharmacol Exp Ther. 1999 Jan;288(1):286-94. J Pharmacol Exp Ther. 1999. PMID: 9862783

9

Effect of age on leukotriene B4 production in guinea pig whole blood.

Spaethe SM, Scaife CL, Pechous PA, VanAlstyne EL. Spaethe SM, et al. Biochem Pharmacol. 1992 Feb 18;43(4):837-43. doi: 10.1016/0006-2952(92)90251-d. Biochem Pharmacol. 1992. PMID: 1311591

10

Pulmonary actions of LY255283, a leukotriene B4 receptor antagonist.

Silbaugh SA, Stengel PW, Cockerham SL, Roman CR, Saussy DL Jr, Spaethe SM, Goodson T Jr, Herron DK, Fleisch JH. Silbaugh SA, et al. Among authors: spaethe sm. Eur J Pharmacol. 1992 Nov 13;223(1):57-64. doi: 10.1016/0014-2999(92)90818-o. Eur J Pharmacol. 1992. PMID: 1335877

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