Tomich JM - Search Results

1

A synthetic peptide derived from glycine-gated Cl- channel induces transepithelial Cl- and fluid secretion.

Wallace DP, Tomich JM, Iwamoto T, Henderson K, Grantham JJ, Sullivan LP. Wallace DP, et al. Among authors: tomich jm. Am J Physiol. 1997 May;272(5 Pt 1):C1672-9. doi: 10.1152/ajpcell.1997.272.5.C1672. Am J Physiol. 1997. PMID: 9176159

2

A synthetic peptide based on a glycine-gated chloride channel induces a novel chloride conductance in isolated epithelial cells.

Mitchell KE, Iwamoto T, Tomich J, Freeman LC. Mitchell KE, et al. Biochim Biophys Acta. 2000 Jun 1;1466(1-2):47-60. doi: 10.1016/s0005-2736(00)00170-x. Biochim Biophys Acta. 2000. PMID: 10825430 Free article.

3

Aqueous solubilization of transmembrane peptide sequences with retention of membrane insertion and function.

Tomich JM, Wallace D, Henderson K, Mitchell KE, Radke G, Brandt R, Ambler CA, Scott AJ, Grantham J, Sullivan L, Iwamoto T. Tomich JM, et al. Biophys J. 1998 Jan;74(1):256-67. doi: 10.1016/S0006-3495(98)77784-7. Biophys J. 1998. PMID: 9449327 Free PMC article.

4

A synthetic channel-forming peptide induces Cl(-) secretion: modulation by Ca(2+)-dependent K(+) channels.

Wallace DP, Tomich JM, Eppler JW, Iwamoto T, Grantham JJ, Sullivan LP. Wallace DP, et al. Among authors: tomich jm. Biochim Biophys Acta. 2000 Mar 15;1464(1):69-82. doi: 10.1016/s0005-2736(99)00248-5. Biochim Biophys Acta. 2000. PMID: 10704921 Free article.

5

NH(2)-terminal modification of a channel-forming peptide increases capacity for epithelial anion secretion.

Broughman JR, Mitchell KE, Sedlacek RL, Iwamoto T, Tomich JM, Schultz BD. Broughman JR, et al. Among authors: tomich jm. Am J Physiol Cell Physiol. 2001 Mar;280(3):C451-8. doi: 10.1152/ajpcell.2001.280.3.C451. Am J Physiol Cell Physiol. 2001. PMID: 11171563 Free article.

In Ussing chamber experiments, apical N-K(4)-M2GlyR (250 microM) increased transepithelial short-circuit current (I(sc)) by 7.7 +/- 1.7 and 10.6 +/- 0.9 microA/cm(2) in Madin-Darby canine kidney and T84 cell monolayers, respectively; these values are significantly greater than th …

In Ussing chamber experiments, apical N-K(4)-M2GlyR (250 microM) increased transepithelial short-circuit current (I(sc)) by 7.7 +/- 1.7 and …

6

Distinct structural elements that direct solution aggregation and membrane assembly in the channel-forming peptide M2GlyR.

Broughman JR, Shank LP, Takeguchi W, Schultz BD, Iwamoto T, Mitchell KE, Tomich JM. Broughman JR, et al. Among authors: tomich jm. Biochemistry. 2002 Jun 11;41(23):7350-8. doi: 10.1021/bi016053q. Biochemistry. 2002. PMID: 12044167

7

Activity and structural comparisons of solution associating and monomeric channel-forming peptides derived from the glycine receptor m2 segment.

Cook GA, Prakash O, Zhang K, Shank LP, Takeguchi WA, Robbins A, Gong YX, Iwamoto T, Schultz BD, Tomich JM. Cook GA, et al. Among authors: tomich jm. Biophys J. 2004 Mar;86(3):1424-35. doi: 10.1016/S0006-3495(04)74212-5. Biophys J. 2004. PMID: 14990471 Free PMC article.

8

Channel-forming peptide modulates transepithelial electrical conductance and solute permeability.

Broughman JR, Brandt RM, Hastings C, Iwamoto T, Tomich JM, Schultz BD. Broughman JR, et al. Among authors: tomich jm. Am J Physiol Cell Physiol. 2004 Jun;286(6):C1312-23. doi: 10.1152/ajpcell.00426.2002. Am J Physiol Cell Physiol. 2004. PMID: 15151917 Free article.

9

Epithelial barrier modulation by a channel forming peptide.

Somasekharan S, Brandt R, Iwamoto T, Tomich JM, Schultz BD. Somasekharan S, et al. Among authors: tomich jm. J Membr Biol. 2008 Mar;222(1):17-30. doi: 10.1007/s00232-008-9099-3. J Membr Biol. 2008. PMID: 18418541

10

Structural implications of placing cationic residues at either the NH2- or COOH-terminus in a pore-forming synthetic peptide.

Broughman JR, Shank LP, Prakash O, Schultz BD, Iwamoto T, Tomich JM, Mitchell K. Broughman JR, et al. Among authors: tomich jm. J Membr Biol. 2002 Nov 15;190(2):93-103. doi: 10.1007/s00232-002-1027-3. J Membr Biol. 2002. PMID: 12474074

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