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Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists.
Lautala S, Provenzani R, Tarvainen I, Sirna K, Karhu ST, Grazhdankin E, Lehtinen AK, Sa'd H, Koivuniemi A, Xhaard H, Tuominen RK, Talman V, Bunker A, Yli-Kauhaluoma J. Lautala S, et al. Among authors: tuominen rk. J Med Chem. 2023 Apr 13;66(7):4588-4602. doi: 10.1021/acs.jmedchem.2c01448. Epub 2023 Apr 3. J Med Chem. 2023. PMID: 37010933 Free PMC article.
Glial cell line-derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo.
Mahato AK, Kopra J, Renko JM, Visnapuu T, Korhonen I, Pulkkinen N, Bespalov MM, Domanskyi A, Ronken E, Piepponen TP, Voutilainen MH, Tuominen RK, Karelson M, Sidorova YA, Saarma M. Mahato AK, et al. Among authors: tuominen rk. Mov Disord. 2020 Feb;35(2):245-255. doi: 10.1002/mds.27943. Epub 2019 Dec 16. Mov Disord. 2020. PMID: 31840869 Free PMC article.
117 results