Abnormal polarization and axon outgrowth in retinal ganglion cells lacking the POU-domain transcription factor Brn-3b.
Wang SW, Gan L, Martin SE, Klein WH.
Wang SW, et al. Among authors: gan l.
Mol Cell Neurosci. 2000 Aug;16(2):141-56. doi: 10.1006/mcne.2000.0860.
Mol Cell Neurosci. 2000.
PMID: 10924257
Without Brn-3b, RGCs commit to their fate and migrate to the ganglion cell layer, but most cells die during fetal development. An earlier report (L. Gan et al., 1999, Dev. Biol. 210, 469-480) suggested that cell death was caused by abnormal axon formation. ...
Without Brn-3b, RGCs commit to their fate and migrate to the ganglion cell layer, but most cells die during fetal development. An earlier re …