McNeil KA - Search Results

1

Introduction of spacer peptides N-terminal to a cleavage recognition motif in recombinant fusion proteins can improve site-specific cleavage.

Polyak SW, Forsberg G, Forbes BE, McNeil KA, Aplin SE, Wallace JC. Polyak SW, et al. Among authors: mcneil ka. Protein Eng. 1997 Jun;10(6):615-9. doi: 10.1093/protein/10.6.615. Protein Eng. 1997. PMID: 9278273

2

Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.

Francis GL, Aplin SE, Milner SJ, McNeil KA, Ballard FJ, Wallace JC. Francis GL, et al. Among authors: mcneil ka. Biochem J. 1993 Aug 1;293 ( Pt 3)(Pt 3):713-9. doi: 10.1042/bj2930713. Biochem J. 1993. PMID: 7688957 Free PMC article.

3

Localization of an insulin-like growth factor (IGF) binding site of bovine IGF binding protein-2 using disulfide mapping and deletion mutation analysis of the C-terminal domain.

Forbes BE, Turner D, Hodge SJ, McNeil KA, Forsberg G, Wallace JC. Forbes BE, et al. Among authors: mcneil ka. J Biol Chem. 1998 Feb 20;273(8):4647-52. doi: 10.1074/jbc.273.8.4647. J Biol Chem. 1998. PMID: 9468524 Free article.

4

A novel binding site for the human insulin-like growth factor-II (IGF-II)/mannose 6-phosphate receptor on IGF-II.

Delaine C, Alvino CL, McNeil KA, Mulhern TD, Gauguin L, De Meyts P, Jones EY, Brown J, Wallace JC, Forbes BE. Delaine C, et al. Among authors: mcneil ka. J Biol Chem. 2007 Jun 29;282(26):18886-94. doi: 10.1074/jbc.M700531200. Epub 2007 May 2. J Biol Chem. 2007. PMID: 17475626 Free article.

5

Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency.

Francis GL, Ross M, Ballard FJ, Milner SJ, Senn C, McNeil KA, Wallace JC, King R, Wells JR. Francis GL, et al. Among authors: mcneil ka. J Mol Endocrinol. 1992 Jun;8(3):213-23. doi: 10.1677/jme.0.0080213. J Mol Endocrinol. 1992. PMID: 1378742

6

Production of a human epidermal growth factor fusion protein and its degradation in rat gastrointestinal flushings.

Xian CJ, Upton Z, Goddard C, Shoubridge CA, McNeil KA, Wallace JC, Read LC, Francis GL. Xian CJ, et al. Among authors: mcneil ka. J Mol Endocrinol. 1996 Feb;16(1):89-97. doi: 10.1677/jme.0.0160089. J Mol Endocrinol. 1996. PMID: 8672237

7

Contribution of residues A54 and L55 of the human insulin-like growth factor-II (IGF-II) A domain to Type 2 IGF receptor binding specificity.

Forbe BE, McNeil KA, Scott CD, Surinya KH, Cosgrove LJ, Wallace JC. Forbe BE, et al. Among authors: mcneil ka. Growth Factors. 2001;19(3):163-73. doi: 10.3109/08977190109001084. Growth Factors. 2001. PMID: 11811790

8

Interaction of insulin-like growth factor (IGF)-I and -II with IGF binding protein-2: mapping the binding surfaces by nuclear magnetic resonance.

Carrick FE, Hinds MG, McNeil KA, Wallace JC, Forbes BE, Norton RS. Carrick FE, et al. Among authors: mcneil ka. J Mol Endocrinol. 2005 Jun;34(3):685-98. doi: 10.1677/jme.1.01756. J Mol Endocrinol. 2005. PMID: 15956340

9

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.

Soh CL, McNeil K, Owczarek CM, Hardy MP, Fabri LJ, Pearse M, Delaine CA, Forbes BE. Soh CL, et al. Br J Cancer. 2014 Jun 10;110(12):2855-64. doi: 10.1038/bjc.2014.232. Epub 2014 May 22. Br J Cancer. 2014. PMID: 24853186 Free PMC article.

10

Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis.

Forbes BE, Hartfield PJ, McNeil KA, Surinya KH, Milner SJ, Cosgrove LJ, Wallace JC. Forbes BE, et al. Among authors: mcneil ka. Eur J Biochem. 2002 Feb;269(3):961-8. doi: 10.1046/j.0014-2956.2001.02735.x. Eur J Biochem. 2002. PMID: 11846798 Free article.

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