Evans JM - Search Results

1

Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures.

Upton N, Blackburn TP, Campbell CA, Cooper D, Evans ML, Herdon HJ, King PD, Ray AM, Stean TO, Chan WN, Evans JM, Thompson M. Upton N, et al. Among authors: evans jm, evans ml. Br J Pharmacol. 1997 Aug;121(8):1679-86. doi: 10.1038/sj.bjp.0701330. Br J Pharmacol. 1997. PMID: 9283703 Free PMC article.

2

Synthesis of novel trans-4-(substituted-benzamido)-3,4-dihydro-2H-benzo[b]-pyran-3-ol derivatives as potential anticonvulsant agents with a distinctive binding profile.

Chan WN, Evans JM, Hadley MS, Herdon HJ, Jerman JC, Morgan HK, Stean TO, Thompson M, Upton N, Vong AK. Chan WN, et al. Among authors: evans jm. J Med Chem. 1996 Nov 8;39(23):4537-9. doi: 10.1021/jm960535w. J Med Chem. 1996. PMID: 8917640 No abstract available.

3

Characterization of the binding of [3H]-SB-204269, a radiolabelled form of the new anticonvulsant SB-204269, to a novel binding site in rat brain membranes.

Herdon HJ, Jerman JC, Stean TO, Middlemiss DN, Chan WN, Vong AK, Evans JM, Thompson M, Upton N. Herdon HJ, et al. Among authors: evans jm. Br J Pharmacol. 1997 Aug;121(8):1687-91. doi: 10.1038/sj.bjp.0701331. Br J Pharmacol. 1997. PMID: 9283704 Free PMC article.

4

Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)- 3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent.

Chan WN, Evans JM, Hadley MS, Herdon HJ, Jerman JC, Parsons AA, Read SJ, Stean TO, Thompson M, Upton N. Chan WN, et al. Among authors: evans jm. Bioorg Med Chem Lett. 1999 Jan 18;9(2):285-90. doi: 10.1016/s0960-894x(98)00728-8. Bioorg Med Chem Lett. 1999. PMID: 10021946

5

Synthesis and antihypertensive activity of 3-[(substituted-carbonyl)amino]-2H-1-benzopyrans.

Cassidy F, Evans JM, Hadley MS, Haladij AH, Leach PE, Stemp G. Cassidy F, et al. Among authors: evans jm. J Med Chem. 1992 May 1;35(9):1623-7. doi: 10.1021/jm00087a018. J Med Chem. 1992. PMID: 1578490

6

Separation of the enantiomers of some potassium channel activators using an alpha 1-acid glycoprotein column.

Evans JM, Smith RJ, Stemp G. Evans JM, et al. J Chromatogr. 1992 Oct 9;623(1):163-7. doi: 10.1016/0021-9673(92)85312-h. J Chromatogr. 1992. PMID: 1452627

7

Synthesis and antihypertensive activity of 4-(substituted-carbonylamino)-2H-1-benzopyrans.

Ashwood VA, Cassidy F, Coldwell MC, Evans JM, Hamilton TC, Howlett DR, Smith DM, Stemp G. Ashwood VA, et al. Among authors: evans jm. J Med Chem. 1990 Sep;33(9):2667-72. doi: 10.1021/jm00171a051. J Med Chem. 1990. PMID: 2391705

8

Synthesis and antihypertensive activity of pyran oxygen and amide nitrogen replacement analogues of the potassium channel activator cromakalim.

Ashwood VA, Cassidy F, Evans JM, Gagliardi S, Stemp G. Ashwood VA, et al. Among authors: evans jm. J Med Chem. 1991 Nov;34(11):3261-7. doi: 10.1021/jm00115a015. J Med Chem. 1991. PMID: 1659637

9

Variation in the aromatic ring of cromakalim: antihypertensive activity of pyranopyridines and 6-alkyl-2H-1-benzopyrans.

Burrell G, Cassidy F, Evans JM, Lightowler D, Stemp G. Burrell G, et al. Among authors: evans jm. J Med Chem. 1990 Nov;33(11):3023-7. doi: 10.1021/jm00173a018. J Med Chem. 1990. PMID: 2231601

10

Potassium channel activators: pharmacological methods, models, and structure-activity relationships.

Evans JM, Taylor SG. Evans JM, et al. Prog Med Chem. 1994;31:411-46. doi: 10.1016/s0079-6468(08)70026-2. Prog Med Chem. 1994. PMID: 8029480 Review. No abstract available.

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