Allan PW - Search Results

1

In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase.

Parker WB, King SA, Allan PW, Bennett LL Jr, Secrist JA 3rd, Montgomery JA, Gilbert KS, Waud WR, Wells AH, Gillespie GY, Sorscher EJ. Parker WB, et al. Among authors: allan pw. Hum Gene Ther. 1997 Sep 20;8(14):1637-44. doi: 10.1089/hum.1997.8.14-1637. Hum Gene Ther. 1997. PMID: 9322865

2

Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.

Parker WB, Allan PW, Hassan AE, Secrist JA 3rd, Sorscher EJ, Waud WR. Parker WB, et al. Among authors: allan pw. Cancer Gene Ther. 2003 Jan;10(1):23-9. doi: 10.1038/sj.cgt.7700520. Cancer Gene Ther. 2003. PMID: 12489025

3

Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.

Hong JS, Waud WR, Levasseur DN, Townes TM, Wen H, McPherson SA, Moore BA, Bebok Z, Allan PW, Secrist JA 3rd, Parker WB, Sorscher EJ. Hong JS, et al. Among authors: allan pw. Cancer Res. 2004 Sep 15;64(18):6610-5. doi: 10.1158/0008-5472.CAN-04-0012. Cancer Res. 2004. PMID: 15374975

4

Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.

Bharara S, Sorscher EJ, Gillespie GY, Lindsey JR, Hong JS, Curlee KV, Allan PW, Gadi VK, Alexander SA, Secrist JA 3rd, Parker WB, Waud WR. Bharara S, et al. Among authors: allan pw. Hum Gene Ther. 2005 Mar;16(3):339-47. doi: 10.1089/hum.2005.16.339. Hum Gene Ther. 2005. PMID: 15812229

5

Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.

Parker WB, Allan PW, Ealick SE, Sorscher EJ, Hassan AE, Silamkoti AV, Fowler AT, Waud WR, Secrist JA 3rd. Parker WB, et al. Among authors: allan pw. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):387-92. doi: 10.1081/ncn-200059807. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247956

6

Regioselective metalation of 6-methylpurines: synthesis of fluoromethyl purines and related nucleosides for suicide gene therapy of cancer.

Hassan AE, Parker WB, Allan PW, Secrist JA 3rd. Hassan AE, et al. Among authors: allan pw. Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):642-56. doi: 10.1080/15257770903091938. Nucleosides Nucleotides Nucleic Acids. 2009. PMID: 20183607

7

Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides.

Hassan AE, Abou-Elkhair RA, Riordan JM, Allan PW, Parker WB, Khare R, Waud WR, Montgomery JA, Secrist JA 3rd. Hassan AE, et al. Among authors: allan pw. Eur J Med Chem. 2012 Jan;47(1):167-74. doi: 10.1016/j.ejmech.2011.10.039. Epub 2011 Nov 4. Eur J Med Chem. 2012. PMID: 22112758 Free PMC article.

8

In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.

Sorscher EJ, Hong JS, Allan PW, Waud WR, Parker WB. Sorscher EJ, et al. Among authors: allan pw. Cancer Chemother Pharmacol. 2012 Aug;70(2):321-9. doi: 10.1007/s00280-012-1908-9. Epub 2012 Jul 4. Cancer Chemother Pharmacol. 2012. PMID: 22760227 Free PMC article.

9

6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase.

Hassan AEA, Abou-Elkhair RAI, Parker WB, Allan PW, Secrist JA 3rd. Hassan AEA, et al. Among authors: allan pw. Eur J Med Chem. 2016 Jan 27;108:616-622. doi: 10.1016/j.ejmech.2015.12.029. Epub 2015 Dec 17. Eur J Med Chem. 2016. PMID: 26724729

10

6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases.

Hassan AE, Abou-Elkhair RA, Parker WB, Allan PW, Secrist JA 3rd. Hassan AE, et al. Among authors: allan pw. Bioorg Chem. 2016 Apr;65:9-16. doi: 10.1016/j.bioorg.2015.12.006. Epub 2015 Dec 24. Bioorg Chem. 2016. PMID: 26745284

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