Mehta ND - Search Results

1

A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43).

Eckman CB, Mehta ND, Crook R, Perez-tur J, Prihar G, Pfeiffer E, Graff-Radford N, Hinder P, Yager D, Zenk B, Refolo LM, Prada CM, Younkin SG, Hutton M, Hardy J. Eckman CB, et al. Among authors: mehta nd. Hum Mol Genet. 1997 Nov;6(12):2087-9. doi: 10.1093/hmg/6.12.2087. Hum Mol Genet. 1997. PMID: 9328472

2

Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells.

Refolo LM, Eckman C, Prada CM, Yager D, Sambamurti K, Mehta N, Hardy J, Younkin SG. Refolo LM, et al. J Neurochem. 1999 Dec;73(6):2383-8. doi: 10.1046/j.1471-4159.1999.0732383.x. J Neurochem. 1999. PMID: 10582597 Free article.

3

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M. Mehta ND, et al. Ann Neurol. 1998 Feb;43(2):256-8. doi: 10.1002/ana.410430217. Ann Neurol. 1998. PMID: 9485068

4

A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.

Crook R, Verkkoniemi A, Perez-Tur J, Mehta N, Baker M, Houlden H, Farrer M, Hutton M, Lincoln S, Hardy J, Gwinn K, Somer M, Paetau A, Kalimo H, Ylikoski R, Pöyhönen M, Kucera S, Haltia M. Crook R, et al. Nat Med. 1998 Apr;4(4):452-5. doi: 10.1038/nm0498-452. Nat Med. 1998. PMID: 9546792

5

Truncated presenilin 2 derived from differentially spliced mRNA does not affect the ratio of amyloid beta-peptide 1-42/1-40.

Grünberg J, Walter J, Eckman C, Capell A, Schindzielorz A, Younkin S, Mehta N, Hardy J, Haass C. Grünberg J, et al. Neuroreport. 1998 Oct 5;9(14):3293-9. doi: 10.1097/00001756-199810050-00027. Neuroreport. 1998. PMID: 9831466

6

Cloning and characterization of the presenilin-2 gene promoter.

Pennypacker KR, Fuldner R, Xu R, Hernandez H, Dawbarn D, Mehta N, Perez-Tur J, Baker M, Hutton M. Pennypacker KR, et al. Brain Res Mol Brain Res. 1998 May;56(1-2):57-65. doi: 10.1016/s0169-328x(98)00028-x. Brain Res Mol Brain Res. 1998. PMID: 9602061

7

Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein.

Ko L, Mehta ND, Farrer M, Easson C, Hussey J, Yen S, Hardy J, Yen SH. Ko L, et al. Among authors: mehta nd. J Neurochem. 2000 Dec;75(6):2546-54. doi: 10.1046/j.1471-4159.2000.0752546.x. J Neurochem. 2000. PMID: 11080208 Free article.

8

Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p.

Gwinn-Hardy K, Mehta ND, Farrer M, Maraganore D, Muenter M, Yen SH, Hardy J, Dickson DW. Gwinn-Hardy K, et al. Among authors: mehta nd. Acta Neuropathol. 2000 Jun;99(6):663-72. doi: 10.1007/s004010051177. Acta Neuropathol. 2000. PMID: 10867800

9

Widespread alterations of alpha-synuclein in multiple system atrophy.

Dickson DW, Liu W, Hardy J, Farrer M, Mehta N, Uitti R, Mark M, Zimmerman T, Golbe L, Sage J, Sima A, D'Amato C, Albin R, Gilman S, Yen SH. Dickson DW, et al. Am J Pathol. 1999 Oct;155(4):1241-51. doi: 10.1016/s0002-9440(10)65226-1. Am J Pathol. 1999. PMID: 10514406 Free PMC article.

10

Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis.

Tanii H, Ankarcrona M, Flood F, Nilsberth C, Mehta ND, Perez-Tur J, Winblad B, Benedikz E, Cowburn RF. Tanii H, et al. Among authors: mehta nd. Neuroscience. 2000;95(2):593-601. doi: 10.1016/s0306-4522(99)00432-7. Neuroscience. 2000. PMID: 10658639

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