Refolo LM - Search Results

1

A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43).

Eckman CB, Mehta ND, Crook R, Perez-tur J, Prihar G, Pfeiffer E, Graff-Radford N, Hinder P, Yager D, Zenk B, Refolo LM, Prada CM, Younkin SG, Hutton M, Hardy J. Eckman CB, et al. Among authors: refolo lm. Hum Mol Genet. 1997 Nov;6(12):2087-9. doi: 10.1093/hmg/6.12.2087. Hum Mol Genet. 1997. PMID: 9328472

2

Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells.

Refolo LM, Eckman C, Prada CM, Yager D, Sambamurti K, Mehta N, Hardy J, Younkin SG. Refolo LM, et al. J Neurochem. 1999 Dec;73(6):2383-8. doi: 10.1046/j.1471-4159.1999.0732383.x. J Neurochem. 1999. PMID: 10582597 Free article.

3

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M. Mehta ND, et al. Among authors: refolo lm. Ann Neurol. 1998 Feb;43(2):256-8. doi: 10.1002/ana.410430217. Ann Neurol. 1998. PMID: 9485068

4

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.

Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479

5

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein.

Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG. Sambamurti K, et al. Among authors: refolo lm. J Biol Chem. 1999 Sep 17;274(38):26810-4. doi: 10.1074/jbc.274.38.26810. J Biol Chem. 1999. PMID: 10480887 Free article.

6

Bacterial expression, purification, and functional mapping of the amyloid beta/A4 protein precursor.

Roch JM, Shapiro IP, Sundsmo MP, Otero DA, Refolo LM, Robakis NK, Saitoh T. Roch JM, et al. Among authors: refolo lm. J Biol Chem. 1992 Feb 5;267(4):2214-21. J Biol Chem. 1992. PMID: 1346393 Free article.

7

Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes.

Zhao J, Paganini L, Mucke L, Gordon M, Refolo L, Carman M, Sinha S, Oltersdorf T, Lieberburg I, McConlogue L. Zhao J, et al. J Biol Chem. 1996 Dec 6;271(49):31407-11. doi: 10.1074/jbc.271.49.31407. J Biol Chem. 1996. PMID: 8940150 Free article.

8

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes.

Duff K, Knight H, Refolo LM, Sanders S, Yu X, Picciano M, Malester B, Hutton M, Adamson J, Goedert M, Burki K, Davies P. Duff K, et al. Among authors: refolo lm. Neurobiol Dis. 2000 Apr;7(2):87-98. doi: 10.1006/nbdi.1999.0279. Neurobiol Dis. 2000. PMID: 10783293

9

Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.

Gandhi S, Refolo LM, Sambamurti K. Gandhi S, et al. Among authors: refolo lm. J Mol Neurosci. 2004;24(1):137-43. doi: 10.1385/JMN:24:1:137. J Mol Neurosci. 2004. PMID: 15314262

10

Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins.

Pappolla MA, Sambamurti K, Efthimiopoulos S, Refolo L, Omar RA, Robakis NK. Pappolla MA, et al. Neurosci Lett. 1995 Jun 9;192(2):105-8. doi: 10.1016/0304-3940(95)11627-9. Neurosci Lett. 1995. PMID: 7675314

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