Blakley RL - Search Results

1

A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugs.

Galipeau J, Benaim E, Spencer HT, Blakley RL, Sorrentino BP. Galipeau J, et al. Among authors: blakley rl. Hum Gene Ther. 1997 Oct 10;8(15):1773-83. doi: 10.1089/hum.1997.8.15-1773. Hum Gene Ther. 1997. PMID: 9358027

2

A gene transfer strategy for making bone marrow cells resistant to trimetrexate.

Spencer HT, Sleep SE, Rehg JE, Blakley RL, Sorrentino BP. Spencer HT, et al. Among authors: blakley rl. Blood. 1996 Mar 15;87(6):2579-87. Blood. 1996. PMID: 8630426 Free article.

3

Mutations in the gene for human dihydrofolate reductase: an unlikely cause of clinical relapse in pediatric leukemia after therapy with methotrexate.

Spencer HT, Sorrentino BP, Pui CH, Chunduru SK, Sleep SE, Blakley RL. Spencer HT, et al. Among authors: blakley rl. Leukemia. 1996 Mar;10(3):439-46. Leukemia. 1996. PMID: 8642859

4

Coding region-specific destabilization of mRNA transcripts attenuates expression from retroviral vectors containing class 1 aldehyde dehydrogenase cDNAs.

Bunting KD, Webb M, Giorgianni F, Galipeau J, Blakley RL, Townsend AJ, Sorrentino BP. Bunting KD, et al. Among authors: blakley rl. Hum Gene Ther. 1997 Sep 1;8(13):1531-43. doi: 10.1089/hum.1997.8.13-1531. Hum Gene Ther. 1997. PMID: 9322086

5

Sensitization of hematopoietic stem and progenitor cells to trimetrexate using nucleoside transport inhibitors.

Allay JA, Spencer HT, Wilkinson SL, Belt JA, Blakley RL, Sorrentino BP. Allay JA, et al. Among authors: blakley rl. Blood. 1997 Nov 1;90(9):3546-54. Blood. 1997. PMID: 9345038 Free article.

6

Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants.

Patel M, Sleep SE, Lewis WS, Spencer HT, Mareya SM, Sorrentino BP, Blakley RL. Patel M, et al. Among authors: blakley rl. Hum Gene Ther. 1997 Nov 20;8(17):2069-77. doi: 10.1089/hum.1997.8.17-2069. Hum Gene Ther. 1997. PMID: 9414255

7

In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application.

Blakley RL, Sorrentino BP. Blakley RL, et al. Hum Mutat. 1998;11(4):259-63. doi: 10.1002/(SICI)1098-1004(1998)11:4<259::AID-HUMU1>3.0.CO;2-W. Hum Mutat. 1998. PMID: 9554740 Review.

8

Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase.

Mareya SM, Sorrentino BP, Blakley RL. Mareya SM, et al. Among authors: blakley rl. Cancer Gene Ther. 1998 Jul-Aug;5(4):225-35. Cancer Gene Ther. 1998. PMID: 9694074

9

In vivo selection of retrovirally transduced hematopoietic stem cells.

Allay JA, Persons DA, Galipeau J, Riberdy JM, Ashmun RA, Blakley RL, Sorrentino BP. Allay JA, et al. Among authors: blakley rl. Nat Med. 1998 Oct;4(10):1136-43. doi: 10.1038/2632. Nat Med. 1998. PMID: 9771746

10

In vivo selection of hematopoietic stem cells transduced with DHFR-expressing retroviral vectors.

Sorrentino BP, Allay JA, Blakley RL. Sorrentino BP, et al. Among authors: blakley rl. Prog Exp Tumor Res. 1999;36:143-61. doi: 10.1159/000061994. Prog Exp Tumor Res. 1999. PMID: 10386071 Review. No abstract available.

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