Mulcahy RT - Search Results

1

Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan.

Bailey HH, Ripple G, Tutsch KD, Arzoomanian RZ, Alberti D, Feierabend C, Mahvi D, Schink J, Pomplun M, Mulcahy RT, Wilding G. Bailey HH, et al. Among authors: mulcahy rt. J Natl Cancer Inst. 1997 Dec 3;89(23):1789-96. doi: 10.1093/jnci/89.23.1789. J Natl Cancer Inst. 1997. PMID: 9392620 Clinical Trial.

2

A phase I study of SR-2508 and cyclophosphamide administered by intravenous injection.

Bailey H, Mulcahy RT, Tutsch KD, Rozental JM, Alberti D, Arzoomanian RZ, Tombes MB, Trump DL, Wilding G. Bailey H, et al. Among authors: mulcahy rt. Cancer Res. 1991 Feb 15;51(4):1099-104. Cancer Res. 1991. PMID: 1825475 Clinical Trial.

3

Transfection of complementary DNAs for the heavy and light subunits of human gamma-glutamylcysteine synthetase results in an elevation of intracellular glutathione and resistance to melphalan.

Mulcahy RT, Bailey HH, Gipp JJ. Mulcahy RT, et al. Cancer Res. 1995 Nov 1;55(21):4771-5. Cancer Res. 1995. PMID: 7585502

4

Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione.

Bailey HH, Mulcahy RT, Tutsch KD, Arzoomanian RZ, Alberti D, Tombes MB, Wilding G, Pomplun M, Spriggs DR. Bailey HH, et al. Among authors: mulcahy rt. J Clin Oncol. 1994 Jan;12(1):194-205. doi: 10.1200/JCO.1994.12.1.194. J Clin Oncol. 1994. PMID: 8270977 Clinical Trial.

5

Increase in gamma-glutamylcysteine synthetase activity and steady-state messenger RNA levels in melphalan-resistant DU-145 human prostate carcinoma cells expressing elevated glutathione levels.

Bailey HH, Gipp JJ, Ripple M, Wilding G, Mulcahy RT. Bailey HH, et al. Among authors: mulcahy rt. Cancer Res. 1992 Sep 15;52(18):5115-8. Cancer Res. 1992. PMID: 1355406

6

Up-regulation of gamma-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels.

Mulcahy RT, Bailey HH, Gipp JJ. Mulcahy RT, et al. Cancer Chemother Pharmacol. 1994;34(1):67-71. doi: 10.1007/BF00686114. Cancer Chemother Pharmacol. 1994. PMID: 7513621

7

Increased expression of gamma-glutamyl transpeptidase in transfected tumor cells and its relationship to drug sensitivity.

Bailey HH, Gipp JJ, Mulcahy RT. Bailey HH, et al. Among authors: mulcahy rt. Cancer Lett. 1994 Dec 9;87(2):163-70. doi: 10.1016/0304-3835(94)90218-6. Cancer Lett. 1994. PMID: 7812936

8

Characteristics of the glutathione/glutathione-S-transferase detoxification system in melphalan resistant human prostate cancer cells.

Ripple M, Mulcahy RT, Wilding G. Ripple M, et al. Among authors: mulcahy rt. J Urol. 1993 Jul;150(1):209-14. doi: 10.1016/s0022-5347(17)35448-4. J Urol. 1993. PMID: 8510259

9

Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues.

Gipp JJ, Bailey HH, Mulcahy RT. Gipp JJ, et al. Among authors: mulcahy rt. Biochem Biophys Res Commun. 1995 Jan 17;206(2):584-9. doi: 10.1006/bbrc.1995.1083. Biochem Biophys Res Commun. 1995. PMID: 7826375

10

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence.

Mulcahy RT, Wartman MA, Bailey HH, Gipp JJ. Mulcahy RT, et al. J Biol Chem. 1997 Mar 14;272(11):7445-54. doi: 10.1074/jbc.272.11.7445. J Biol Chem. 1997. PMID: 9054446 Free article.

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