Langer T - Search Results

1

Azinyl and diazinyl hydrazones derived from aryl N-heteroaryl ketones: synthesis and antiproliferative activity.

Easmon J, Heinisch G, Pürstinger G, Langer T, Osterreicher JK, Grunicke HH, Hofmann J. Easmon J, et al. Among authors: langer t. J Med Chem. 1997 Dec 19;40(26):4420-5. doi: 10.1021/jm970255w. J Med Chem. 1997. PMID: 9435912

2

Novel, potent, and selective 5-HT3 receptor antagonists based on the arylpiperazine skeleton: synthesis, structure, biological activity, and comparative molecular field analysis studies.

Anzini M, Cappelli A, Vomero S, Giorgi G, Langer T, Hamon M, Merahi N, Emerit BM, Cagnotto A, Skorupska M, et al. Anzini M, et al. Among authors: langer t. J Med Chem. 1995 Jul 7;38(14):2692-704. doi: 10.1021/jm00014a021. J Med Chem. 1995. PMID: 7629808

3

Computer-aided molecular modeling, synthesis, and biological evaluation of 8-(benzyloxy)-2-phenylpyrazolo[4,3-c]quinoline as a novel benzodiazepine receptor agonist ligand.

Wang CG, Langer T, Kamath PG, Gu ZQ, Skolnick P, Fryer RI. Wang CG, et al. Among authors: langer t. J Med Chem. 1995 Mar 17;38(6):950-7. doi: 10.1021/jm00006a014. J Med Chem. 1995. PMID: 7699711

4

On the bioisosteric potential of diazines: diazine analogues of the combined thromboxane A2 receptor antagonist and synthetase inhibitor Ridogrel.

Heinisch G, Holzer W, Kunz F, Langer T, Lukavsky P, Pechlaner C, Weissenberger H. Heinisch G, et al. Among authors: langer t. J Med Chem. 1996 Sep 27;39(20):4058-64. doi: 10.1021/jm960341g. J Med Chem. 1996. PMID: 8831771

5

Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification.

Krovat EM, Langer T. Krovat EM, et al. Among authors: langer t. J Med Chem. 2003 Feb 27;46(5):716-26. doi: 10.1021/jm021032v. J Med Chem. 2003. PMID: 12593652

6

Chemical function based pharmacophore generation of endothelin-A selective receptor antagonists.

Funk OF, Kettmann V, Drimal J, Langer T. Funk OF, et al. Among authors: langer t. J Med Chem. 2004 May 20;47(11):2750-60. doi: 10.1021/jm031041j. J Med Chem. 2004. PMID: 15139753

7

Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products.

Rollinger JM, Hornick A, Langer T, Stuppner H, Prast H. Rollinger JM, et al. Among authors: langer t. J Med Chem. 2004 Dec 2;47(25):6248-54. doi: 10.1021/jm049655r. J Med Chem. 2004. PMID: 15566295

8

Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.

Laggner C, Schieferer C, Fiechtner B, Poles G, Hoffmann RD, Glossmann H, Langer T, Moebius FF. Laggner C, et al. Among authors: langer t. J Med Chem. 2005 Jul 28;48(15):4754-64. doi: 10.1021/jm049073+. J Med Chem. 2005. PMID: 16033255

9

Pharmacophore modeling, docking, and principal component analysis based clustering: combined computer-assisted approaches to identify new inhibitors of the human rhinovirus coat protein.

Steindl TM, Crump CE, Hayden FG, Langer T. Steindl TM, et al. Among authors: langer t. J Med Chem. 2005 Oct 6;48(20):6250-60. doi: 10.1021/jm050343d. J Med Chem. 2005. PMID: 16190752

10

The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening.

Schuster D, Maurer EM, Laggner C, Nashev LG, Wilckens T, Langer T, Odermatt A. Schuster D, et al. Among authors: langer t. J Med Chem. 2006 Jun 15;49(12):3454-66. doi: 10.1021/jm0600794. J Med Chem. 2006. PMID: 16759088

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