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Page 1
Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists.
Micheli F, Fabio RD, Cavanni P, Rimland JM, Capelli AM, Chiamulera C, Corsi M, Corti C, Donati D, Feriani A, Ferraguti F, Maffeis M, Missio A, Ratti E, Paio A, Pachera R, Quartaroli M, Reggiani A, Sabbatini FM, Trist DG, Ugolini A, Vitulli G. Micheli F, et al. Among authors: donati d. Bioorg Med Chem. 2003 Jan 17;11(2):171-83. doi: 10.1016/s0968-0896(02)00424-8. Bioorg Med Chem. 2003. PMID: 12470711
Enantiomerically pure tetrahydroquinoline derivatives as in vivo potent antagonists of the glycine binding site associated to the NMDA receptor.
Di Fabio R, Tranquillini E, Bertani B, Alvaro G, Micheli F, Sabbatini F, Pizzi MD, Pentassuglia G, Pasquarello A, Messeri T, Donati D, Ratti E, Arban R, Dal Forno G, Reggiani A, Barnaby RJ. Di Fabio R, et al. Among authors: donati d. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3863-6. doi: 10.1016/j.bmcl.2003.06.001. Bioorg Med Chem Lett. 2003. PMID: 14552796
Substituted indole-2-carboxylates as in vivo potent antagonists acting as the strychnine-insensitive glycine binding site.
Di Fabio R, Capelli AM, Conti N, Cugola A, Donati D, Feriani A, Gastaldi P, Gaviraghi G, Hewkin CT, Micheli F, Missio A, Mugnaini M, Pecunioso A, Quaglia AM, Ratti E, Rossi L, Tedesco G, Trist DG, Reggiani A. Di Fabio R, et al. Among authors: donati d. J Med Chem. 1997 Mar 14;40(6):841-50. doi: 10.1021/jm960644a. J Med Chem. 1997. PMID: 9083472
2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: further characterization of 3,5-dimethyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester and structure-activity relationships.
Micheli F, Di Fabio R, Bordi F, Cavallini P, Cavanni P, Donati D, Faedo S, Maffeis M, Sabbatini FM, Tarzia G, Tranquillini ME. Micheli F, et al. Among authors: donati d. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2113-8. doi: 10.1016/s0960-894x(03)00396-2. Bioorg Med Chem Lett. 2003. PMID: 12798316
Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists.
Di Fabio R, Giovannini R, Bertani B, Borriello M, Bozzoli A, Donati D, Falchi A, Ghirlanda D, Leslie CP, Pecunioso A, Rumboldt G, Spada S. Di Fabio R, et al. Among authors: donati d. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1749-52. doi: 10.1016/j.bmcl.2005.11.104. Epub 2005 Dec 20. Bioorg Med Chem Lett. 2006. PMID: 16364642
New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part 2: [g]-fused and hetero-fused systems.
Micheli F, Bonanomi G, Braggio S, Capelli AM, Damiani F, Di Fabio R, Donati D, Gentile G, Hamprecht D, Perini O, Petrone M, Tedesco G, Terreni S, Worby A, Heidbreder C. Micheli F, et al. Among authors: donati d. Bioorg Med Chem Lett. 2008 Feb 1;18(3):908-12. doi: 10.1016/j.bmcl.2007.12.042. Epub 2008 Jan 4. Bioorg Med Chem Lett. 2008. PMID: 18178090
Dopamine D(3) receptor antagonists: The quest for a potentially selective PET ligand. Part two: Lead optimization.
Micheli F, Holmes I, Arista L, Bonanomi G, Braggio S, Cardullo F, Di Fabio R, Donati D, Gentile G, Hamprecht D, Terreni S, Heidbreder C, Savoia C, Griffante C, Worby A. Micheli F, et al. Among authors: donati d. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4011-3. doi: 10.1016/j.bmcl.2009.06.028. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19553113
675 results