Williams JW - Search Results

1

Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production.

Siemasko K, Chong AS, Jäck HM, Gong H, Williams JW, Finnegan A. Siemasko K, et al. Among authors: williams jw. J Immunol. 1998 Feb 15;160(4):1581-8. J Immunol. 1998. PMID: 9469413

2

Leflunomide, a novel immunosuppressive agent. The mechanism of inhibition of T cell proliferation.

Chong AS, Finnegan A, Jiang X, Gebel H, Sankary HN, Foster P, Williams JW. Chong AS, et al. Among authors: williams jw. Transplantation. 1993 Jun;55(6):1361-6. doi: 10.1097/00007890-199306000-00028. Transplantation. 1993. PMID: 8390735

3

Effects of leflunomide and other immunosuppressive agents on T cell proliferation in vitro.

Chong AS, Rezai K, Gebel HM, Finnegan A, Foster P, Xu X, Williams JW. Chong AS, et al. Among authors: williams jw. Transplantation. 1996 Jan 15;61(1):140-5. doi: 10.1097/00007890-199601150-00026. Transplantation. 1996. PMID: 8560553

4

Regulation of B cell function by the immunosuppressive agent leflunomide.

Siemasko KF, Chong AS, Williams JW, Bremer EG, Finnegan A. Siemasko KF, et al. Among authors: williams jw. Transplantation. 1996 Feb 27;61(4):635-42. doi: 10.1097/00007890-199602270-00020. Transplantation. 1996. PMID: 8610393

5

Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation.

Xu X, Williams JW, Gong H, Finnegan A, Chong AS. Xu X, et al. Among authors: williams jw. Biochem Pharmacol. 1996 Aug 23;52(4):527-34. doi: 10.1016/0006-2952(96)00303-6. Biochem Pharmacol. 1996. PMID: 8759024

6

The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms.

Elder RT, Xu X, Williams JW, Gong H, Finnegan A, Chong AS. Elder RT, et al. Among authors: williams jw. J Immunol. 1997 Jul 1;159(1):22-7. J Immunol. 1997. PMID: 9200434

7

In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice.

Xu X, Blinder L, Shen J, Gong H, Finnegan A, Williams JW, Chong AS. Xu X, et al. Among authors: williams jw. J Immunol. 1997 Jul 1;159(1):167-74. J Immunol. 1997. PMID: 9200452

8

Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action.

Xu X, Gong H, Blinder L, Shen J, Williams JW, Chong AS. Xu X, et al. Among authors: williams jw. J Pharmacol Exp Ther. 1997 Nov;283(2):869-75. J Pharmacol Exp Ther. 1997. PMID: 9353408

9

Modification of humoral responses by the combination of leflunomide and cyclosporine in Lewis rats transplanted with hamster hearts.

Chong AS, Ma LL, Shen J, Blinder L, Yin DP, Williams JW. Chong AS, et al. Among authors: williams jw. Transplantation. 1997 Dec 27;64(12):1650-7. doi: 10.1097/00007890-199712270-00004. Transplantation. 1997. PMID: 9422397

10

In vitro and in vivo mechanisms of action of the antiproliferative and immunosuppressive agent, brequinar sodium.

Xu X, Williams JW, Shen J, Gong H, Yin DP, Blinder L, Elder RT, Sankary H, Finnegan A, Chong AS. Xu X, et al. Among authors: williams jw. J Immunol. 1998 Jan 15;160(2):846-53. J Immunol. 1998. PMID: 9551920

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