Schelen AM - Search Results

1

Proliferation signaling and activation of Shc, p21Ras, and Myc via tyrosine 764 of human granulocyte colony-stimulating factor receptor.

de Koning JP, Soede-Bobok AA, Schelen AM, Smith L, van Leeuwen D, Santini V, Burgering BM, Bos JL, Lowenberg B, Touw IP. de Koning JP, et al. Among authors: schelen am. Blood. 1998 Mar 15;91(6):1924-33. Blood. 1998. PMID: 9490675 Free article.

2

Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia.

Dong F, Hoefsloot LH, Schelen AM, Broeders CA, Meijer Y, Veerman AJ, Touw IP, Löwenberg B. Dong F, et al. Among authors: schelen am. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4480-4. doi: 10.1073/pnas.91.10.4480. Proc Natl Acad Sci U S A. 1994. PMID: 7514305 Free PMC article.

3

Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes.

de Koning JP, Schelen AM, Dong F, van Buitenen C, Burgering BM, Bos JL, Löwenberg B, Touw IP. de Koning JP, et al. Among authors: schelen am. Blood. 1996 Jan 1;87(1):132-40. Blood. 1996. PMID: 8547634 Free article.

4

The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation.

de Koning JP, Dong F, Smith L, Schelen AM, Barge RM, van der Plas DC, Hoefsloot LH, Löwenberg B, Touw IP. de Koning JP, et al. Among authors: schelen am. Blood. 1996 Feb 15;87(4):1335-42. Blood. 1996. PMID: 8608222 Free article.

5

Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration.

Ward AC, Hermans MH, Smith L, van Aesch YM, Schelen AM, Antonissen C, Touw IP. Ward AC, et al. Among authors: schelen am. Blood. 1999 Jan 1;93(1):113-24. Blood. 1999. PMID: 9864153 Free article.

6

Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia.

Ward AC, van Aesch YM, Schelen AM, Touw IP. Ward AC, et al. Among authors: schelen am. Blood. 1999 Jan 15;93(2):447-58. Blood. 1999. PMID: 9885206 Free article.

7

Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment.

Ward AC, van Aesch YM, Gits J, Schelen AM, de Koning JP, van Leeuwen D, Freedman MH, Touw IP. Ward AC, et al. Among authors: schelen am. J Exp Med. 1999 Aug 16;190(4):497-507. doi: 10.1084/jem.190.4.497. J Exp Med. 1999. PMID: 10449521 Free PMC article.

8

STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1).

de Koning JP, Soede-Bobok AA, Ward AC, Schelen AM, Antonissen C, van Leeuwen D, Löwenberg B, Touw IP. de Koning JP, et al. Among authors: schelen am. Oncogene. 2000 Jul 6;19(29):3290-8. doi: 10.1038/sj.onc.1203627. Oncogene. 2000. PMID: 10918585

9

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.

Abbas S, Lugthart S, Kavelaars FG, Schelen A, Koenders JE, Zeilemaker A, van Putten WJ, Rijneveld AW, Löwenberg B, Valk PJ. Abbas S, et al. Blood. 2010 Sep 23;116(12):2122-6. doi: 10.1182/blood-2009-11-250878. Epub 2010 Jun 10. Blood. 2010. PMID: 20538800 Free article.

10

Human primary T lymphocytes have a low capacity to amplify MLV-based amphotropic RCR and the virions produced are largely noninfectious.

Ebeling SB, Simonetti ER, Borst HP, Blok A, Schelen AM, Braakman E, Ederveen J, Hagenbeek A. Ebeling SB, et al. Among authors: schelen am. Gene Ther. 2003 Oct;10(21):1800-6. doi: 10.1038/sj.gt.3302080. Gene Ther. 2003. PMID: 12960969

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