Dower WJ - Search Results

1

Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1.

Johnson DL, Farrell FX, Barbone FP, McMahon FJ, Tullai J, Hoey K, Livnah O, Wrighton NC, Middleton SA, Loughney DA, Stura EA, Dower WJ, Mulcahy LS, Wilson IA, Jolliffe LK. Johnson DL, et al. Among authors: dower wj. Biochemistry. 1998 Mar 17;37(11):3699-710. doi: 10.1021/bi971956y. Biochemistry. 1998. PMID: 9521688

2

Small peptides as potent mimetics of the protein hormone erythropoietin.

Wrighton NC, Farrell FX, Chang R, Kashyap AK, Barbone FP, Mulcahy LS, Johnson DL, Barrett RW, Jolliffe LK, Dower WJ. Wrighton NC, et al. Among authors: dower wj. Science. 1996 Jul 26;273(5274):458-64. doi: 10.1126/science.273.5274.458. Science. 1996. PMID: 8662529

3

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.

Livnah O, Stura EA, Johnson DL, Middleton SA, Mulcahy LS, Wrighton NC, Dower WJ, Jolliffe LK, Wilson IA. Livnah O, et al. Among authors: dower wj. Science. 1996 Jul 26;273(5274):464-71. doi: 10.1126/science.273.5274.464. Science. 1996. PMID: 8662530

4

Increased potency of an erythropoietin peptide mimetic through covalent dimerization.

Wrighton NC, Balasubramanian P, Barbone FP, Kashyap AK, Farrell FX, Jolliffe LK, Barrett RW, Dower WJ. Wrighton NC, et al. Among authors: dower wj. Nat Biotechnol. 1997 Nov;15(12):1261-5. doi: 10.1038/nbt1197-1261. Nat Biotechnol. 1997. PMID: 9359108

5

Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.

Cwirla SE, Balasubramanian P, Duffin DJ, Wagstrom CR, Gates CM, Singer SC, Davis AM, Tansik RL, Mattheakis LC, Boytos CM, Schatz PJ, Baccanari DP, Wrighton NC, Barrett RW, Dower WJ. Cwirla SE, et al. Among authors: dower wj. Science. 1997 Jun 13;276(5319):1696-9. doi: 10.1126/science.276.5319.1696. Science. 1997. PMID: 9180079

6

Selective enrichment and characterization of high affinity ligands from collections of random peptides on filamentous phage.

Barrett RW, Cwirla SE, Ackerman MS, Olson AM, Peters EA, Dower WJ. Barrett RW, et al. Among authors: dower wj. Anal Biochem. 1992 Aug 1;204(2):357-64. doi: 10.1016/0003-2697(92)90252-3. Anal Biochem. 1992. PMID: 1443536

7

Peptides on phage: a vast library of peptides for identifying ligands.

Cwirla SE, Peters EA, Barrett RW, Dower WJ. Cwirla SE, et al. Among authors: dower wj. Proc Natl Acad Sci U S A. 1990 Aug;87(16):6378-82. doi: 10.1073/pnas.87.16.6378. Proc Natl Acad Sci U S A. 1990. PMID: 2201029 Free PMC article.

8

Generation and screening of an oligonucleotide-encoded synthetic peptide library.

Needels MC, Jones DG, Tate EH, Heinkel GL, Kochersperger LM, Dower WJ, Barrett RW, Gallop MA. Needels MC, et al. Among authors: dower wj. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10700-4. doi: 10.1073/pnas.90.22.10700. Proc Natl Acad Sci U S A. 1993. PMID: 7504279 Free PMC article.

9

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries.

Gallop MA, Barrett RW, Dower WJ, Fodor SP, Gordon EM. Gallop MA, et al. Among authors: dower wj. J Med Chem. 1994 Apr 29;37(9):1233-51. doi: 10.1021/jm00035a001. J Med Chem. 1994. PMID: 8176700 Review. No abstract available.

10

Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions.

Gordon EM, Barrett RW, Dower WJ, Fodor SP, Gallop MA. Gordon EM, et al. Among authors: dower wj. J Med Chem. 1994 May 13;37(10):1385-401. doi: 10.1021/jm00036a001. J Med Chem. 1994. PMID: 8182695 Review. No abstract available.

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