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Ethnobotanical-directed discovery of the antihyperglycemic properties of cryptolepine: its isolation from Cryptolepis sanguinolenta, synthesis, and in vitro and in vivo activities.
Bierer DE, Fort DM, Mendez CD, Luo J, Imbach PA, Dubenko LG, Jolad SD, Gerber RE, Litvak J, Lu Q, Zhang P, Reed MJ, Waldeck N, Bruening RC, Noamesi BK, Hector RF, Carlson TJ, King SR. Bierer DE, et al. Among authors: mendez cd. J Med Chem. 1998 Mar 12;41(6):894-901. doi: 10.1021/jm9704816. J Med Chem. 1998. PMID: 9526563
Cryptolepis sanguinolenta: an ethnobotanical approach to drug discovery and the isolation of a potentially useful new antihyperglycaemic agent.
Luo J, Fort DM, Carlson TJ, Noamesi BK, nii-Amon-Kotei D, King SR, Tsai J, Quan J, Hobensack C, Lapresca P, Waldeck N, Mendez CD, Jolad SD, Bierer DE, Reaven GM. Luo J, et al. Among authors: mendez cd. Diabet Med. 1998 May;15(5):367-74. doi: 10.1002/(SICI)1096-9136(199805)15:5<367::AID-DIA576>3.0.CO;2-G. Diabet Med. 1998. PMID: 9609357 Clinical Trial.
Antihyperglycemic furanosesquiterpenes from commiphora myrrha.
Ubillas RP, Mendez CD, Jolad SD, Luo J, King SR, Carlson TJ, Fort DM. Ubillas RP, et al. Among authors: mendez cd. Planta Med. 1999 Dec;65(8):778-9. doi: 10.1055/s-2006-960870. Planta Med. 1999. PMID: 10630129 No abstract available.
Novel antihyperglycemic terpenoid-quinones from Pycnanthus angolensis.
Fort DM, Ubillas RP, Mendez CD, Jolad SD, Inman WD, Carney JR, Chen JL, Ianiro TT, Hasbun C, Bruening RC, Luo J, Reed MJ, Iwu M, Carlson TJ, King SR, Bierer DE, Cooper R. Fort DM, et al. Among authors: mendez cd. J Org Chem. 2000 Oct 6;65(20):6534-9. doi: 10.1021/jo000568q. J Org Chem. 2000. PMID: 11052098
Antihyperglycemic acetylenic glucosides from Bidens pilosa.
Ubillas RP, Mendez CD, Jolad SD, Luo J, King SR, Carlson TJ, Fort DM. Ubillas RP, et al. Among authors: mendez cd. Planta Med. 2000 Feb;66(1):82-3. doi: 10.1055/s-0029-1243117. Planta Med. 2000. PMID: 10705745
Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.
Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J. Zhu L, et al. J Org Chem. 2005 Jan 21;70(2):631-8. doi: 10.1021/jo0483623. J Org Chem. 2005. PMID: 15651811 Free PMC article.
180 results