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The binding site of a specific aminoglycoside binding RNA molecule.
Cho J, Hamasaki K, Rando RR. Cho J, et al. Biochemistry. 1998 Apr 7;37(14):4985-92. doi: 10.1021/bi972757h. Biochemistry. 1998. PMID: 9538017
A small (40 nucleotides) stem-loop derivative (J6f1) of a specific aminoglycoside-binding RNA aptamer, containing a 3 nt and a 1 nt bulge, has previously been shown to stoichiometrically bind tobramycin with a dissociation constant of approximately 5 nM [Hamasaki, K., Killian, …
A small (40 nucleotides) stem-loop derivative (J6f1) of a specific aminoglycoside-binding RNA aptamer, containing a 3 nt and a 1 nt bulge, h …
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