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531 results

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Page 1
The discovery of LY293111, a novel, potent and orally active leukotriene B4 receptor antagonist of the biphenylphenol class.
Sofia MJ, Floreancig P, Bach N, Baker SR, Nelson K, Sawyer JS, Baldwin R, Cockerham SL, Fleisch JH, Froelich LL, Jackson WT, Marder P, Roman CR, Saussy DL Jr, Silbaugh SA, Spaethe SM, Stengel PW. Sofia MJ, et al. Among authors: baker sr. Adv Exp Med Biol. 1997;400A:381-6. doi: 10.1007/978-1-4615-5325-0_51. Adv Exp Med Biol. 1997. PMID: 9547580 No abstract available.
Synthetic and structure/activity studies on acid-substituted 2-arylphenols: discovery of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]-propoxy]phenoxy]benzoic acid, a high-affinity leukotriene B4 receptor antagonist.
Sawyer JS, Bach NJ, Baker SR, Baldwin RF, Borromeo PS, Cockerham SL, Fleisch JH, Floreancig P, Froelich LL, Jackson WT, et al. Sawyer JS, et al. Among authors: baker sr. J Med Chem. 1995 Oct 27;38(22):4411-32. doi: 10.1021/jm00022a006. J Med Chem. 1995. PMID: 7473568
o-phenylphenols: potent and orally active leukotriene B4 receptor antagonists.
Sofia MJ, Floreancig P, Bach NJ, Baker SR, Cockerham SL, Fleisch JH, Froelich LL, Jackson WT, Marder P, Roman CR, et al. Sofia MJ, et al. Among authors: baker sr. J Med Chem. 1993 Nov 26;36(24):3978-81. doi: 10.1021/jm00076a029. J Med Chem. 1993. PMID: 7902871 No abstract available.
Aerosolized LTB4 produces delayed onset increases in pulmonary gas trapping.
Silbaugh SA, Stengel PW, Cockerham SL, Froelich LL, Bendele AM, Rippy MK, Baker SR, Sofia MJ, Jackson WT. Silbaugh SA, et al. Among authors: baker sr. Prostaglandins Leukot Essent Fatty Acids. 1996 Feb;54(2):115-21. doi: 10.1016/s0952-3278(96)90068-x. Prostaglandins Leukot Essent Fatty Acids. 1996. PMID: 8848430
4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists.
Baker SR, Bleakman D, Ezquerra J, Ballyk BA, Deverill M, Ho K, Kamboj RK, Collado I, Domínguez C, Escribano A, Mateo AI, Pedregal C, Rubio A. Baker SR, et al. Bioorg Med Chem Lett. 2000 Aug 21;10(16):1807-10. doi: 10.1016/s0960-894x(00)00346-2. Bioorg Med Chem Lett. 2000. PMID: 10969973
Biarylpropylsulfonamides as novel, potent potentiators of 2-amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic acid (AMPA) receptors.
Ornstein PL, Zimmerman DM, Arnold MB, Bleisch TJ, Cantrell B, Simon R, Zarrinmayeh H, Baker SR, Gates M, Tizzano JP, Bleakman D, Mandelzys A, Jarvie KR, Ho K, Deverill M, Kamboj RK. Ornstein PL, et al. Among authors: baker sr. J Med Chem. 2000 Nov 16;43(23):4354-8. doi: 10.1021/jm0002836. J Med Chem. 2000. PMID: 11087558 No abstract available.
531 results