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Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.
Schiffer IB, Gebhard S, Heimerdinger CK, Heling A, Hast J, Wollscheid U, Seliger B, Tanner B, Gilbert S, Beckers T, Baasner S, Brenner W, Spangenberg C, Prawitt D, Trost T, Schreiber WG, Zabel B, Thelen M, Lehr HA, Oesch F, Hengstler JG. Schiffer IB, et al. Among authors: spangenberg c. Cancer Res. 2003 Nov 1;63(21):7221-31. Cancer Res. 2003. PMID: 14612517
4-Epidoxycycline: an alternative to doxycycline to control gene expression in conditional mouse models.
Eger K, Hermes M, Uhlemann K, Rodewald S, Ortwein J, Brulport M, Bauer AW, Schormann W, Lupatsch F, Schiffer IB, Heimerdinger CK, Gebhard S, Spangenberg C, Prawitt D, Trost T, Zabel B, Sauer C, Tanner B, Kolbl H, Krugel U, Franke H, Illes P, Madaj-Sterba P, Bockamp EO, Beckers T, Hengstler JG. Eger K, et al. Among authors: spangenberg c. Biochem Biophys Res Commun. 2004 Oct 22;323(3):979-86. doi: 10.1016/j.bbrc.2004.08.187. Biochem Biophys Res Commun. 2004. PMID: 15381096
Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression.
Prawitt D, Enklaar T, Klemm G, Gärtner B, Spangenberg C, Winterpacht A, Higgins M, Pelletier J, Zabel B. Prawitt D, et al. Among authors: spangenberg c. Hum Mol Genet. 2000 Jan 22;9(2):203-16. doi: 10.1093/hmg/9.2.203. Hum Mol Genet. 2000. PMID: 10607831
Of mice and models: improved animal models for biomedical research.
Bockamp E, Maringer M, Spangenberg C, Fees S, Fraser S, Eshkind L, Oesch F, Zabel B. Bockamp E, et al. Among authors: spangenberg c. Physiol Genomics. 2002 Dec 3;11(3):115-32. doi: 10.1152/physiolgenomics.00067.2002. Epub 2002 Dec 3. Physiol Genomics. 2002. PMID: 12464688 Review.
28 results