Okamura H - Search Results

1

Regulation of interferon-gamma production by IL-12 and IL-18.

Okamura H, Kashiwamura S, Tsutsui H, Yoshimoto T, Nakanishi K. Okamura H, et al. Curr Opin Immunol. 1998 Jun;10(3):259-64. doi: 10.1016/s0952-7915(98)80163-5. Curr Opin Immunol. 1998. PMID: 9638361 Review.

2

Pathophysiological roles of interleukin-18 in inflammatory liver diseases.

Tsutsui H, Matsui K, Okamura H, Nakanishi K. Tsutsui H, et al. Among authors: okamura h. Immunol Rev. 2000 Apr;174:192-209. doi: 10.1034/j.1600-0528.2002.017418.x. Immunol Rev. 2000. PMID: 10807517 Review.

3

LPS-stimulated SJL macrophages produce IL-12 and IL-18 that inhibit IgE production in vitro by induction of IFN-gamma production from CD3intIL-2R beta+ T cells.

Yoshimoto T, Nagai N, Ohkusu K, Ueda H, Okamura H, Nakanishi K. Yoshimoto T, et al. Among authors: okamura h. J Immunol. 1998 Aug 1;161(3):1483-92. J Immunol. 1998. PMID: 9686615

4

Interleukin-18: a novel cytokine that augments both innate and acquired immunity.

Okamura H, Tsutsui H, Kashiwamura S, Yoshimoto T, Nakanishi K. Okamura H, et al. Adv Immunol. 1998;70:281-312. doi: 10.1016/s0065-2776(08)60389-2. Adv Immunol. 1998. PMID: 9755340 Review. No abstract available.

5

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.

Yoshimoto T, Takeda K, Tanaka T, Ohkusu K, Kashiwamura S, Okamura H, Akira S, Nakanishi K. Yoshimoto T, et al. Among authors: okamura h. J Immunol. 1998 Oct 1;161(7):3400-7. J Immunol. 1998. PMID: 9759857

6

IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor.

Hyodo Y, Matsui K, Hayashi N, Tsutsui H, Kashiwamura S, Yamauchi H, Hiroishi K, Takeda K, Tagawa Y, Iwakura Y, Kayagaki N, Kurimoto M, Okamura H, Hada T, Yagita H, Akira S, Nakanishi K, Higashino K. Hyodo Y, et al. Among authors: okamura h. J Immunol. 1999 Feb 1;162(3):1662-8. J Immunol. 1999. PMID: 9973427

7

IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock.

Sakao Y, Takeda K, Tsutsui H, Kaisho T, Nomura F, Okamura H, Nakanishi K, Akira S. Sakao Y, et al. Among authors: okamura h. Int Immunol. 1999 Mar;11(3):471-80. doi: 10.1093/intimm/11.3.471. Int Immunol. 1999. PMID: 10221659

8

High IL-18 (interferon-gamma inducing factor) concentration in a purine nucleoside phosphorylase deficient patient.

Yamamoto T, Moriwaki Y, Matsui K, Takahashi S, Tsutsui H, Yoshimoto T, Okamura H, Nakanishi K, Kurosawa Y, Yamaguchi S, Sasaki Y, Higashino K. Yamamoto T, et al. Among authors: okamura h. Arch Dis Child. 1999 Aug;81(2):179-80. doi: 10.1136/adc.81.2.179. Arch Dis Child. 1999. PMID: 10490534 Free PMC article.

9

IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils.

Yoshimoto T, Tsutsui H, Tominaga K, Hoshino K, Okamura H, Akira S, Paul WE, Nakanishi K. Yoshimoto T, et al. Among authors: okamura h. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13962-6. doi: 10.1073/pnas.96.24.13962. Proc Natl Acad Sci U S A. 1999. PMID: 10570181 Free PMC article.

10

IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells.

Tominaga K, Yoshimoto T, Torigoe K, Kurimoto M, Matsui K, Hada T, Okamura H, Nakanishi K. Tominaga K, et al. Among authors: okamura h. Int Immunol. 2000 Feb;12(2):151-60. doi: 10.1093/intimm/12.2.151. Int Immunol. 2000. PMID: 10653850

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