Leff P - Search Results

1

Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.

Berg KA, Maayani S, Goldfarb J, Scaramellini C, Leff P, Clarke WP. Berg KA, et al. Among authors: leff p. Mol Pharmacol. 1998 Jul;54(1):94-104. Mol Pharmacol. 1998. PMID: 9658194

2

A three-state receptor model of agonist action.

Leff P, Scaramellini C, Law C, McKechnie K. Leff P, et al. Trends Pharmacol Sci. 1997 Oct;18(10):355-62. doi: 10.1016/s0165-6147(97)01105-x. Trends Pharmacol Sci. 1997. PMID: 9357320 Review.

3

A three-state receptor model: predictions of multiple agonist pharmacology for the same receptor type.

Scaramellini C, Leff P. Scaramellini C, et al. Among authors: leff p. Ann N Y Acad Sci. 1998 Dec 15;861:97-103. doi: 10.1111/j.1749-6632.1998.tb10179.x. Ann N Y Acad Sci. 1998. PMID: 9928245

4

Analysis of agonist-agonist interactions: the crucial influence of curve shape.

Scaramellini C, Bennett G, Leff P. Scaramellini C, et al. Among authors: leff p. J Pharmacol Toxicol Methods. 1997 Apr;37(3):167-78. doi: 10.1016/s1056-8719(97)00015-4. J Pharmacol Toxicol Methods. 1997. PMID: 9253753

5

Promiscuity, pre-coupling and instability.

Leff P, Scaramellini C. Leff P, et al. Trends Pharmacol Sci. 1998 Jan;19(1):13. doi: 10.1016/s0165-6147(97)01150-4. Trends Pharmacol Sci. 1998. PMID: 9509895 No abstract available.

6

Theoretical implications of receptor coupling to multiple G proteins based on analysis of a three-state model.

Scaramellini C, Leff P. Scaramellini C, et al. Among authors: leff p. Methods Enzymol. 2002;343:17-29. doi: 10.1016/s0076-6879(02)43125-4. Methods Enzymol. 2002. PMID: 11665565 No abstract available.

7

Estimation of the efficacy and affinity of the beta 2-adrenoceptor agonist salmeterol in guinea-pig trachea.

Dougall IG, Harper D, Jackson DM, Leff P. Dougall IG, et al. Among authors: leff p. Br J Pharmacol. 1991 Dec;104(4):1057-61. doi: 10.1111/j.1476-5381.1991.tb12549.x. Br J Pharmacol. 1991. PMID: 1687365 Free PMC article.

8

Further subclassification of ATP receptors based on agonist studies.

O'Connor SE, Dainty IA, Leff P. O'Connor SE, et al. Among authors: leff p. Trends Pharmacol Sci. 1991 Apr;12(4):137-41. doi: 10.1016/0165-6147(91)90530-6. Trends Pharmacol Sci. 1991. PMID: 2063479 Review.

9

Estimation of agonist affinity and efficacy by direct, operational model-fitting.

Leff P, Prentice DJ, Giles H, Martin GR, Wood J. Leff P, et al. J Pharmacol Methods. 1990 May;23(3):225-37. doi: 10.1016/0160-5402(90)90066-t. J Pharmacol Methods. 1990. PMID: 2329803

10

Partial agonist effects of BW A868C, a selective DP receptor antagonist, on Cl- secretion in dog tracheal epithelium.

Liu YJ, Jackson DM, Blackham A, Leff P. Liu YJ, et al. Among authors: leff p. Eur J Pharmacol. 1996 May 23;304(1-3):117-22. doi: 10.1016/0014-2999(96)00129-x. Eur J Pharmacol. 1996. PMID: 8813592

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