Khojasteh-Bakht SC - Search Results

1

(R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 2A6.

Khojasteh-Bakht SC, Koenigs LL, Peter RM, Trager WF, Nelson SD. Khojasteh-Bakht SC, et al. Drug Metab Dispos. 1998 Jul;26(7):701-4. Drug Metab Dispos. 1998. PMID: 9660853

2

Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.

Khojasteh-Bakht SC, Chen W, Koenigs LL, Peter RM, Nelson SD. Khojasteh-Bakht SC, et al. Drug Metab Dispos. 1999 May;27(5):574-80. Drug Metab Dispos. 1999. PMID: 10220485

3

Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones.

Khojasteh-Bakht SC, Nelson SD, Atkins WM. Khojasteh-Bakht SC, et al. Arch Biochem Biophys. 1999 Oct 1;370(1):59-65. doi: 10.1006/abbi.1999.1361. Arch Biochem Biophys. 1999. PMID: 10496977

4

Inhibitory properties of trapping agents: glutathione, potassium cyanide, and methoxylamine, against major human cytochrome p450 isoforms.

Zhang C, Wong S, Delarosa EM, Kenny JR, Halladay JS, Hop CE, Khojasteh-Bakht SC. Zhang C, et al. Among authors: khojasteh bakht sc. Drug Metab Lett. 2009 Apr;3(2):125-9. doi: 10.2174/187231209788654126. Drug Metab Lett. 2009. PMID: 19601875

5

Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

Khojasteh-Bakht SC, Rossulek MI, Fouda HG, Prakash C. Khojasteh-Bakht SC, et al. Xenobiotica. 2003 Dec;33(12):1201-10. doi: 10.1080/00498250310001646362. Xenobiotica. 2003. PMID: 14742142

6

Metabolic stability screen for drug discovery using cassette analysis and column switching.

Halladay JS, Wong S, Jaffer SM, Sinhababu AK, Khojasteh-Bakht SC. Halladay JS, et al. Among authors: khojasteh bakht sc. Drug Metab Lett. 2007 Jan;1(1):67-72. doi: 10.2174/187231207779814364. Drug Metab Lett. 2007. PMID: 19356021

7

Formation of a quinoneimine intermediate of 4-fluoro-N-methylaniline by FMO1: carbon oxidation plus defluorination.

Driscoll JP, Aliagas I, Harris JJ, Halladay JS, Khatib-Shahidi S, Deese A, Segraves N, Khojasteh-Bakht SC. Driscoll JP, et al. Among authors: khojasteh bakht sc. Chem Res Toxicol. 2010 May 17;23(5):861-3. doi: 10.1021/tx1000688. Chem Res Toxicol. 2010. PMID: 20369854

8

Metabolism, pharmacokinetics, tissue distribution, and excretion of [14C]CP-424391 in rats.

Khojasteh-Bakht SC, O'donnell JP, Fouda HG, Potchoiba MJ. Khojasteh-Bakht SC, et al. Drug Metab Dispos. 2005 Jan;33(1):190-9. doi: 10.1124/dmd.104.001065. Epub 2004 Oct 14. Drug Metab Dispos. 2005. PMID: 15486077

9

Metabolism, pharmacokinetics, and excretion of a nonpeptidic substance P receptor antagonist, ezlopitant, in normal healthy male volunteers: characterization of polar metabolites by chemical derivatization with dansyl chloride.

Prakash C, O'Donnell J, Khojasteh-Bakht SC. Prakash C, et al. Among authors: khojasteh bakht sc. Drug Metab Dispos. 2007 Jul;35(7):1071-80. doi: 10.1124/dmd.107.015362. Epub 2007 Apr 12. Drug Metab Dispos. 2007. PMID: 17431029 Clinical Trial.

10

Automated online liquid chromatographic/mass spectrometric metabolic study for prodrug stability.

Lai F, Khojasteh-Bakht SC. Lai F, et al. Among authors: khojasteh bakht sc. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jan 25;814(2):225-32. doi: 10.1016/j.jchromb.2004.10.040. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15639443

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