Talbot DC - Search Results

1

Thymidine phosphorylase moderates thymidine-dependent rescue after exposure to the thymidylate synthase inhibitor ZD1694 (Tomudex) in vitro.

Patterson AV, Talbot DC, Stratford IJ, Harris AL. Patterson AV, et al. Among authors: talbot dc. Cancer Res. 1998 Jul 1;58(13):2737-40. Cancer Res. 1998. PMID: 9661884

2

Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase.

Patterson AV, Zhang H, Moghaddam A, Bicknell R, Talbot DC, Stratford IJ, Harris AL. Patterson AV, et al. Among authors: talbot dc. Br J Cancer. 1995 Sep;72(3):669-75. doi: 10.1038/bjc.1995.392. Br J Cancer. 1995. PMID: 7669579 Free PMC article.

3

A phase II study of etanercept (Enbrel), a tumor necrosis factor alpha inhibitor in patients with metastatic breast cancer.

Madhusudan S, Foster M, Muthuramalingam SR, Braybrooke JP, Wilner S, Kaur K, Han C, Hoare S, Balkwill F, Talbot DC, Ganesan TS, Harris AL. Madhusudan S, et al. Among authors: talbot dc. Clin Cancer Res. 2004 Oct 1;10(19):6528-34. doi: 10.1158/1078-0432.CCR-04-0730. Clin Cancer Res. 2004. PMID: 15475440 Clinical Trial.

4

Phase I study of intrapleural batimastat (BB-94), a matrix metalloproteinase inhibitor, in the treatment of malignant pleural effusions.

Macaulay VM, O'Byrne KJ, Saunders MP, Braybrooke JP, Long L, Gleeson F, Mason CS, Harris AL, Brown P, Talbot DC. Macaulay VM, et al. Among authors: talbot dc. Clin Cancer Res. 1999 Mar;5(3):513-20. Clin Cancer Res. 1999. PMID: 10100701 Clinical Trial.

5

Phase I study of the novel cyclic AMP (cAMP) analogue 8-chloro-cAMP in patients with cancer: toxicity, hormonal, and immunological effects.

Propper DJ, Saunders MP, Salisbury AJ, Long L, O'Byrne KJ, Braybrooke JP, Dowsett M, Taylor M, Talbot DC, Ganesan TS, Harris AL. Propper DJ, et al. Among authors: talbot dc. Clin Cancer Res. 1999 Jul;5(7):1682-9. Clin Cancer Res. 1999. PMID: 10430069 Clinical Trial.

6

Induction of thymidine phosphorylase as a pharmacodynamic end-point in patients with advanced carcinoma treated with 5-fluorouracil, folinic acid and interferon alpha.

Braybrooke JP, Propper DJ, O'Byrne KJ, Koukourakis MI, Patterson AV, Houlbrook S, Love SD, Varcoe S, Taylor M, Ganesan TS, Talbot DC, Harris AL. Braybrooke JP, et al. Among authors: talbot dc. Br J Cancer. 2000 Jul;83(2):219-24. doi: 10.1054/bjoc.2000.1230. Br J Cancer. 2000. PMID: 10901374 Free PMC article. Clinical Trial.

7

A phase II study of razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis.

Braybrooke JP, O'Byrne KJ, Propper DJ, Blann A, Saunders M, Dobbs N, Han C, Woodhull J, Mitchell K, Crew J, Smith K, Stephens R, Ganesan TS, Talbot DC, Harris AL. Braybrooke JP, et al. Among authors: talbot dc. Clin Cancer Res. 2000 Dec;6(12):4697-704. Clin Cancer Res. 2000. PMID: 11156222 Clinical Trial.

8

Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MMI270 (CGS27023A), in patients with advanced solid cancer.

Levitt NC, Eskens FA, O'Byrne KJ, Propper DJ, Denis LJ, Owen SJ, Choi L, Foekens JA, Wilner S, Wood JM, Nakajima M, Talbot DC, Steward WP, Harris AL, Verweij J. Levitt NC, et al. Among authors: talbot dc. Clin Cancer Res. 2001 Jul;7(7):1912-22. Clin Cancer Res. 2001. PMID: 11448904 Clinical Trial.

9

Pharmacokinetic study of cisplatin and infusional etoposide phosphate in advanced breast cancer with correlation of response to topoisomerase IIalpha expression.

Braybrooke JP, Levitt NC, Joel S, Davis T, Madhusudan S, Turley H, Wilner S, Harris AL, Talbot DC. Braybrooke JP, et al. Among authors: talbot dc. Clin Cancer Res. 2003 Oct 15;9(13):4682-8. Clin Cancer Res. 2003. PMID: 14581337

10

Overexpression of human NADPH:cytochrome c (P450) reductase confers enhanced sensitivity to both tirapazamine (SR 4233) and RSU 1069.

Patterson AV, Saunders MP, Chinje EC, Talbot DC, Harris AL, Strafford IJ. Patterson AV, et al. Among authors: talbot dc. Br J Cancer. 1997;76(10):1338-47. doi: 10.1038/bjc.1997.558. Br J Cancer. 1997. PMID: 9374381 Free PMC article.

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