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Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: pestell rg. J Biol Chem. 2004 Jun 4;279(23):24745-56. doi: 10.1074/jbc.M402064200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044451 Free article.
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.
Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: pestell rg. J Biol Chem. 2004 Dec 3;279(49):51630-46. doi: 10.1074/jbc.M409214200. Epub 2004 Sep 7. J Biol Chem. 2004. PMID: 15355971 Free article.
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.
Williams TM, Hassan GS, Li J, Cohen AW, Medina F, Frank PG, Pestell RG, Di Vizio D, Loda M, Lisanti MP. Williams TM, et al. Among authors: pestell rg. J Biol Chem. 2005 Jul 1;280(26):25134-45. doi: 10.1074/jbc.M501186200. Epub 2005 Mar 30. J Biol Chem. 2005. PMID: 15802273 Free article.
pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells.
Lee RJ, Albanese C, Stenger RJ, Watanabe G, Inghirami G, Haines GK 3rd, Webster M, Muller WJ, Brugge JS, Davis RJ, Pestell RG. Lee RJ, et al. Among authors: pestell rg. J Biol Chem. 1999 Mar 12;274(11):7341-50. doi: 10.1074/jbc.274.11.7341. J Biol Chem. 1999. PMID: 10066798 Free article.
p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.
Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. Engelman JA, et al. Among authors: pestell rg. J Biol Chem. 1999 Nov 5;274(45):32333-41. doi: 10.1074/jbc.274.45.32333. J Biol Chem. 1999. PMID: 10542274 Free article.
The cyclin D1 gene is transcriptionally repressed by caveolin-1.
Hulit J, Bash T, Fu M, Galbiati F, Albanese C, Sage DR, Schlegel A, Zhurinsky J, Shtutman M, Ben-Ze'ev A, Lisanti MP, Pestell RG. Hulit J, et al. Among authors: pestell rg. J Biol Chem. 2000 Jul 14;275(28):21203-9. doi: 10.1074/jbc.M000321200. J Biol Chem. 2000. PMID: 10747899 Free article.
Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.
Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP. Zhang W, et al. Among authors: pestell rg. J Biol Chem. 2000 Jul 7;275(27):20717-25. doi: 10.1074/jbc.M909895199. J Biol Chem. 2000. PMID: 10748172 Free article.
493 results