Zhang XG - Search Results

1

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

Chou TC, Zhang XG, Balog A, Su DS, Meng D, Savin K, Bertino JR, Danishefsky SJ. Chou TC, et al. Among authors: zhang xg. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9642-7. doi: 10.1073/pnas.95.16.9642. Proc Natl Acad Sci U S A. 1998. PMID: 9689134 Free PMC article.

2

Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones.

Chou TC, Zhang X, Zhong ZY, Li Y, Feng L, Eng S, Myles DR, Johnson R Jr, Wu N, Yin YI, Wilson RM, Danishefsky SJ. Chou TC, et al. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13157-62. doi: 10.1073/pnas.0804773105. Epub 2008 Aug 28. Proc Natl Acad Sci U S A. 2008. PMID: 18755900 Free PMC article.

3

Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

Chou TC, Zhang XG, Harris CR, Kuduk SD, Balog A, Savin KA, Bertino JR, Danishefsky SJ. Chou TC, et al. Among authors: zhang xg. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15798-802. doi: 10.1073/pnas.95.26.15798. Proc Natl Acad Sci U S A. 1998. PMID: 9861050 Free PMC article.

4

A Novel Aldol Condensation with 2-Methyl-4-pentenal and Its Application to an Improved Total Synthesis of Epothilone B.

Balog A, Harris C, Savin K, Zhang XG, Chou TC, Danishefsky SJ. Balog A, et al. Among authors: zhang xg. Angew Chem Int Ed Engl. 1998 Oct 16;37(19):2675-2678. doi: 10.1002/(SICI)1521-3773(19981016)37:19<2675::AID-ANIE2675>3.0.CO;2-O. Angew Chem Int Ed Engl. 1998. PMID: 29711598

5

Therapeutic cure against human tumor xenografts in nude mice by a microtubule stabilization agent, fludelone, via parenteral or oral route.

Chou TC, Dong H, Zhang X, Tong WP, Danishefsky SJ. Chou TC, et al. Cancer Res. 2005 Oct 15;65(20):9445-54. doi: 10.1158/0008-5472.CAN-05-1014. Cancer Res. 2005. PMID: 16230408

6

Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol.

Chou TC, Dong H, Zhang X, Lei X, Hartung J, Zhang Y, Lee JH, Wilson RM, Danishefsky SJ. Chou TC, et al. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14336-41. doi: 10.1073/pnas.1111332108. Epub 2011 Aug 15. Proc Natl Acad Sci U S A. 2011. PMID: 21844359 Free PMC article.

7

Total synthesis and antitumor activity of 12,13-desoxyepothilone F: an unexpected solvolysis problem at C15, mediated by remote substitution at C21.

Lee CB, Chou TC, Zhang XG, Wang ZG, Kuduk SD, Chappell MD, Stachel SJ, Danishefsky SJ. Lee CB, et al. Among authors: zhang xg. J Org Chem. 2000 Oct 6;65(20):6525-33. doi: 10.1021/jo000617z. J Org Chem. 2000. PMID: 11052097

8

Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker.

Kakadiya R, Dong H, Kumar A, Narsinh D, Zhang X, Chou TC, Lee TC, Shah A, Su TL. Kakadiya R, et al. Bioorg Med Chem. 2010 Mar 15;18(6):2285-2299. doi: 10.1016/j.bmc.2010.01.061. Epub 2010 Feb 4. Bioorg Med Chem. 2010. PMID: 20181487

9

Synthesis and structure-activity relationships of potential anticancer agents: alkylcarbamates of 3-(9-acridinylamino)-5-hydroxymethylaniline.

Su TL, Chen CH, Huang LF, Chen CH, Basu MK, Zhang XG, Chou TC. Su TL, et al. Among authors: zhang xg. J Med Chem. 1999 Nov 18;42(23):4741-8. doi: 10.1021/jm9901226. J Med Chem. 1999. PMID: 10579838

10

Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity.

Bacherikov VA, Chou TC, Dong HJ, Zhang X, Chen CH, Lin YW, Tsai TJ, Lee RZ, Liu LF, Su TL. Bacherikov VA, et al. Bioorg Med Chem. 2005 Jun 2;13(12):3993-4006. doi: 10.1016/j.bmc.2005.03.057. Bioorg Med Chem. 2005. PMID: 15911312

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