Nielsen B - Search Results

1

Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors.

Bräuner-Osborne H, Nielsen B, Krogsgaard-Larsen P. Bräuner-Osborne H, et al. Among authors: nielsen b. Eur J Pharmacol. 1998 Jun 5;350(2-3):311-6. doi: 10.1016/s0014-2999(98)00246-5. Eur J Pharmacol. 1998. PMID: 9696422

2

Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs.

Guldbrandt M, Johansen TN, Frydenvang K, Bräuner-Osborne H, Stensbøl TB, Nielsen B, Karla R, Santi F, Krogsgaard-Larsen P, Madsen U. Guldbrandt M, et al. Among authors: nielsen b. Chirality. 2002 May 5;14(4):351-63. doi: 10.1002/chir.10104. Chirality. 2002. PMID: 11968078

3

2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors.

Johansen TN, Janin YL, Nielsen B, Frydenvang K, Bräuner-Osborne H, Stensbøl TB, Vogensen SB, Madsen U, Krogsgaard-Larsen P. Johansen TN, et al. Among authors: nielsen b. Bioorg Med Chem. 2002 Jul;10(7):2259-66. doi: 10.1016/s0968-0896(02)00041-x. Bioorg Med Chem. 2002. PMID: 11983523

4

Selective agonists at group II metabotropic glutamate receptors: synthesis, stereochemistry, and molecular pharmacology of (S)- and (R)-2-amino-4-(4-hydroxy[1,2,5]thiadiazol-3-yl)butyric acid.

Clausen RP, Bräuner-Osborne H, Greenwood JR, Hermit MB, Stensbøl TB, Nielsen B, Krogsgaard-Larsen P. Clausen RP, et al. Among authors: nielsen b. J Med Chem. 2002 Sep 12;45(19):4240-5. doi: 10.1021/jm020122x. J Med Chem. 2002. PMID: 12213064

5

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.

Brehm L, Greenwood JR, Hansen KB, Nielsen B, Egebjerg J, Stensbøl TB, Bräuner-Osborne H, Sløk FA, Kronborg TT, Krogsgaard-Larsen P. Brehm L, et al. Among authors: nielsen b. J Med Chem. 2003 Apr 10;46(8):1350-8. doi: 10.1021/jm0204441. J Med Chem. 2003. PMID: 12672235

6

Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues.

Valgeirsson J, Christensen JK, Kristensen AS, Pickering DS, Nielsen B, Fischer CH, Bräuner-Osborne H, Nielsen EØ, Krogsgaard-Larsen P, Madsen U. Valgeirsson J, et al. Among authors: nielsen eo, nielsen b. Bioorg Med Chem. 2003 Oct 1;11(20):4341-9. doi: 10.1016/s0968-0896(03)00485-1. Bioorg Med Chem. 2003. PMID: 13129570

7

Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors.

Hermit MB, Greenwood JR, Nielsen B, Bunch L, Jørgensen CG, Vestergaard HT, Stensbøl TB, Sanchez C, Krogsgaard-Larsen P, Madsen U, Bräuner-Osborne H. Hermit MB, et al. Among authors: nielsen b. Eur J Pharmacol. 2004 Feb 23;486(3):241-50. doi: 10.1016/j.ejphar.2003.12.033. Eur J Pharmacol. 2004. PMID: 14985045

8

Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.

Brehm L, Greenwood JR, Sløk FA, Holm MM, Nielsen B, Geneser U, Stensbøl TB, Bräuner-Osborne H, Begtrup M, Egebjerg J, Krogsgaard-Larsen P. Brehm L, et al. Among authors: nielsen b. Chirality. 2004 Aug;16(7):452-66. doi: 10.1002/chir.20060. Chirality. 2004. PMID: 15236343

9

The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.

Clausen RP, Hansen KB, Calí P, Nielsen B, Greenwood JR, Begtrup M, Egebjerg J, Bräuner-Osborne H. Clausen RP, et al. Among authors: nielsen b. Eur J Pharmacol. 2004 Sep 19;499(1-2):35-44. doi: 10.1016/j.ejphar.2004.07.049. Eur J Pharmacol. 2004. PMID: 15363949

10

4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes.

Madsen U, Pickering DS, Nielsen B, Bräuner-Osborne H. Madsen U, et al. Among authors: nielsen b. Neuropharmacology. 2005;49 Suppl 1:114-9. doi: 10.1016/j.neuropharm.2005.05.007. Neuropharmacology. 2005. PMID: 15996690

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