Bohlen P - Search Results

1

Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.

Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin DJ, Bohlen P, Witte L. Zhu Z, et al. Among authors: bohlen p. Cancer Res. 1998 Aug 1;58(15):3209-14. Cancer Res. 1998. PMID: 9699643

2

Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. Int J Cancer. 2002 Jan 20;97(3):393-9. doi: 10.1002/ijc.1634. Int J Cancer. 2002. PMID: 11774295

3

Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability.

Liao F, Doody JF, Overholser J, Finnerty B, Bassi R, Wu Y, Dejana E, Kussie P, Bohlen P, Hicklin DJ. Liao F, et al. Among authors: bohlen p. Cancer Res. 2002 May 1;62(9):2567-75. Cancer Res. 2002. PMID: 11980651

4

Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics.

Zhu Z, Bohlen P, Witte L. Zhu Z, et al. Among authors: bohlen p. Curr Cancer Drug Targets. 2002 Jun;2(2):135-56. doi: 10.2174/1568009023333881. Curr Cancer Drug Targets. 2002. PMID: 12188915 Review.

5

Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity.

Lu D, Shen J, Vil MD, Zhang H, Jimenez X, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. J Biol Chem. 2003 Oct 31;278(44):43496-507. doi: 10.1074/jbc.M307742200. Epub 2003 Aug 12. J Biol Chem. 2003. PMID: 12917408 Free article.

6

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL. Burtrum D, et al. Among authors: bohlen p. Cancer Res. 2003 Dec 15;63(24):8912-21. Cancer Res. 2003. PMID: 14695208

7

Inhibition of both the autocrine and the paracrine growth of human leukemia with a fully human antibody directed against vascular endothelial growth factor receptor 2.

Zhang H, Li Y, Li H, Bassi R, Jimenez X, Witte L, Bohlen P, Hicklin D, Zhu Z. Zhang H, et al. Among authors: bohlen p. Leuk Lymphoma. 2004 Sep;45(9):1887-97. doi: 10.1080/10428190410001712225. Leuk Lymphoma. 2004. PMID: 15223651

8

Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells.

Vincent L, Jin DK, Karajannis MA, Shido K, Hooper AT, Rashbaum WK, Pytowski B, Wu Y, Hicklin DJ, Zhu Z, Bohlen P, Niesvizky R, Rafii S. Vincent L, et al. Among authors: bohlen p. Cancer Res. 2005 Apr 15;65(8):3185-92. doi: 10.1158/0008-5472.CAN-04-3598. Cancer Res. 2005. PMID: 15833849

9

The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma.

Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ. Wu Y, et al. Among authors: bohlen p. Int J Cancer. 2006 Oct 1;119(7):1519-29. doi: 10.1002/ijc.21865. Int J Cancer. 2006. PMID: 16671089

10

Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies.

Lu D, Kussie P, Pytowski B, Persaud K, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. J Biol Chem. 2000 May 12;275(19):14321-30. doi: 10.1074/jbc.275.19.14321. J Biol Chem. 2000. PMID: 10799512 Free article.

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