Zhu Z - Search Results

1

Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.

Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin DJ, Bohlen P, Witte L. Zhu Z, et al. Cancer Res. 1998 Aug 1;58(15):3209-14. Cancer Res. 1998. PMID: 9699643

2

Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.

Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. Cancer Res. 2001 Oct 1;61(19):7002-8. Cancer Res. 2001. PMID: 11585724

3

Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity.

Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig DL, Dias S, Kussie P, Koo H, Kim HJ, Lu D, Liu M, Tejada R, Friedrich M, Bohlen P, Witte L, Rafii S. Zhu Z, et al. Leukemia. 2003 Mar;17(3):604-11. doi: 10.1038/sj.leu.2402831. Leukemia. 2003. PMID: 12646950

4

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy.

Witte L, Hicklin DJ, Zhu Z, Pytowski B, Kotanides H, Rockwell P, Böhlen P. Witte L, et al. Among authors: zhu z. Cancer Metastasis Rev. 1998 Jun;17(2):155-61. doi: 10.1023/a:1006094117427. Cancer Metastasis Rev. 1998. PMID: 9770111 Review.

5

Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody.

Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, Hicklin DJ, Bohlen P, Witte L. Zhu Z, et al. Cancer Lett. 1999 Mar 1;136(2):203-13. doi: 10.1016/s0304-3835(98)00324-3. Cancer Lett. 1999. PMID: 10355750

6

Acquired antagonistic activity of a bispecific diabody directed against two different epitopes on vascular endothelial growth factor receptor 2.

Lu D, Kotanides H, Jimenez X, Zhou Q, Persaud K, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Immunol Methods. 1999 Nov 19;230(1-2):159-71. doi: 10.1016/s0022-1759(99)00135-0. J Immunol Methods. 1999. PMID: 10594363

7

Inhibition of tumor growth and metastasis by targeting tumor-associated angiogenesis with antagonists to the receptors of vascular endothelial growth factor.

Zhu Z, Witte L. Zhu Z, et al. Invest New Drugs. 1999;17(3):195-212. doi: 10.1023/a:1006314501634. Invest New Drugs. 1999. PMID: 10665474 Review.

8

Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies.

Lu D, Kussie P, Pytowski B, Persaud K, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Biol Chem. 2000 May 12;275(19):14321-30. doi: 10.1074/jbc.275.19.14321. J Biol Chem. 2000. PMID: 10799512 Free article.

9

Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration.

Dias S, Hattori K, Zhu Z, Heissig B, Choy M, Lane W, Wu Y, Chadburn A, Hyjek E, Gill M, Hicklin DJ, Witte L, Moore MA, Rafii S. Dias S, et al. Among authors: zhu z. J Clin Invest. 2000 Aug;106(4):511-21. doi: 10.1172/JCI8978. J Clin Invest. 2000. PMID: 10953026 Free PMC article.

10

Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.

Hattori K, Dias S, Heissig B, Hackett NR, Lyden D, Tateno M, Hicklin DJ, Zhu Z, Witte L, Crystal RG, Moore MA, Rafii S. Hattori K, et al. Among authors: zhu z. J Exp Med. 2001 May 7;193(9):1005-14. doi: 10.1084/jem.193.9.1005. J Exp Med. 2001. PMID: 11342585 Free PMC article.

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