Fram R - Search Results

1

Phase I and pharmacokinetic study of the water-soluble dolastatin 15 analog LU103793 in patients with advanced solid malignancies.

Villalona-Calero MA, Baker SD, Hammond L, Aylesworth C, Eckhardt SG, Kraynak M, Fram R, Fischkoff S, Velagapudi R, Toppmeyer D, Razvillas B, Jakimowicz K, Von Hoff DD, Rowinsky E. Villalona-Calero MA, et al. Among authors: fram r. J Clin Oncol. 1998 Aug;16(8):2770-9. doi: 10.1200/JCO.1998.16.8.2770. J Clin Oncol. 1998. PMID: 9704730 Clinical Trial.

2

Phase I and pharmacokinetic study of LU79553, a DNA intercalating bisnaphthalimide, in patients with solid malignancies.

Villalona-Calero MA, Eder JP, Toppmeyer DL, Allen LF, Fram R, Velagapudi R, Myers M, Amato A, Kagen-Hallet K, Razvillas B, Kufe DW, Von Hoff DD, Rowinsky EK. Villalona-Calero MA, et al. Among authors: fram r. J Clin Oncol. 2001 Feb 1;19(3):857-69. doi: 10.1200/JCO.2001.19.3.857. J Clin Oncol. 2001. PMID: 11157040 Clinical Trial.

3

A phase I study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously daily for 5 consecutive days every 3 weeks in patients with advanced solid tumors.

Ebbinghaus S, Rubin E, Hersh E, Cranmer LD, Bonate PL, Fram RJ, Jekunen A, Weitman S, Hammond LA. Ebbinghaus S, et al. Clin Cancer Res. 2005 Nov 1;11(21):7807-16. doi: 10.1158/1078-0432.CCR-05-0909. Clin Cancer Res. 2005. PMID: 16278403 Clinical Trial.

4

Phase I and pharmacokinetic study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously on days 1, 3, and 5 every 3 weeks in patients with advanced solid tumors.

Cunningham C, Appleman LJ, Kirvan-Visovatti M, Ryan DP, Regan E, Vukelja S, Bonate PL, Ruvuna F, Fram RJ, Jekunen A, Weitman S, Hammond LA, Eder JP Jr. Cunningham C, et al. Clin Cancer Res. 2005 Nov 1;11(21):7825-33. doi: 10.1158/1078-0432.CCR-05-0058. Clin Cancer Res. 2005. PMID: 16278405 Clinical Trial.

5

A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion.

Supko JG, Lynch TJ, Clark JW, Fram R, Allen LF, Velagapudi R, Kufe DW, Eder JP Jr. Supko JG, et al. Among authors: fram r. Cancer Chemother Pharmacol. 2000;46(4):319-28. doi: 10.1007/s002800000152. Cancer Chemother Pharmacol. 2000. PMID: 11052630 Clinical Trial.

6

Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors.

Conley BA, Egorin MJ, Tait N, Rosen DM, Sausville EA, Dover G, Fram RJ, Van Echo DA. Conley BA, et al. Among authors: fram rj. Clin Cancer Res. 1998 Mar;4(3):629-34. Clin Cancer Res. 1998. PMID: 9533530 Clinical Trial.

7

Preirradiation chemotherapy of supratentorial malignant primary brain tumors with intracarotid cis-platinum (CDDP) and i.v. BCNU. A phase II trial.

Recht L, Fram RJ, Strauss G, Fitzgerald TJ, Liepman M, Lew R, Kadish S, Sherman D, Wilson J, Greenberger J, et al. Recht L, et al. Among authors: fram rj. Am J Clin Oncol. 1990 Apr;13(2):125-31. doi: 10.1097/00000421-199004000-00008. Am J Clin Oncol. 1990. PMID: 2156417

8

A phase I-II study of combination therapy with thymidine and cytosine arabinoside.

Fram R, Major P, Egan E, Beardsley P, Rosenthal D, Kufe D. Fram R, et al. Cancer Chemother Pharmacol. 1983;11(1):43-7. doi: 10.1007/BF00257416. Cancer Chemother Pharmacol. 1983. PMID: 6883625

9

Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis.

Reimer CL, Agata N, Tammam JG, Bamberg M, Dickerson WM, Kamphaus GD, Rook SL, Milhollen M, Fram R, Kalluri R, Kufe D, Kharbanda S. Reimer CL, et al. Among authors: fram r. Cancer Res. 2002 Feb 1;62(3):789-95. Cancer Res. 2002. PMID: 11830534

10

Inhibition of DNA excision repair and the repair of X-ray-induced DNA damage by cytosine arabinoside and hydroxyurea.

Fram RJ, Kufe DW. Fram RJ, et al. Pharmacol Ther. 1985;31(3):165-76. doi: 10.1016/0163-7258(85)90021-x. Pharmacol Ther. 1985. PMID: 3939629 No abstract available.

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