Klein U - Search Results

1

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci.

Pasqualucci L, Migliazza A, Fracchiolla N, William C, Neri A, Baldini L, Chaganti RS, Klein U, Küppers R, Rajewsky K, Dalla-Favera R. Pasqualucci L, et al. Among authors: klein u. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11816-21. doi: 10.1073/pnas.95.20.11816. Proc Natl Acad Sci U S A. 1998. PMID: 9751748 Free PMC article.

2

Variable-region gene analysis of B-cell subsets derived from a 4-year-old child. Somatically mutated memory B cells accumulate in the peripheral blood already at young age.

Klein U, Küppers R, Rajewsky K. Klein U, et al. Ann N Y Acad Sci. 1995 Sep 29;764:189-91. Ann N Y Acad Sci. 1995. PMID: 7486521 No abstract available.

3

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

Klein U, Küppers R, Rajewsky K. Klein U, et al. J Exp Med. 1994 Oct 1;180(4):1383-93. doi: 10.1084/jem.180.4.1383. J Exp Med. 1994. PMID: 7931072 Free PMC article.

4

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.

Klein U, Küppers R, Rajewsky K. Klein U, et al. Eur J Immunol. 1993 Dec;23(12):3272-7. doi: 10.1002/eji.1830231232. Eur J Immunol. 1993. PMID: 8258343

5

Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes.

Klein U, Klein G, Ehlin-Henriksson B, Rajewsky K, Küppers R. Klein U, et al. Among authors: klein g. Mol Med. 1995 Jul;1(5):495-505. Mol Med. 1995. PMID: 8529116 Free PMC article.

6

Evidence for a large compartment of IgM-expressing memory B cells in humans.

Klein U, Küppers R, Rajewsky K. Klein U, et al. Blood. 1997 Feb 15;89(4):1288-98. Blood. 1997. PMID: 9028952 Free article.

7

Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.

Fischer M, Klein U, Küppers R. Fischer M, et al. Among authors: klein u. J Clin Invest. 1997 Oct 1;100(7):1667-76. doi: 10.1172/JCI119691. J Clin Invest. 1997. PMID: 9312164 Free PMC article.

8

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease.

Goossens T, Klein U, Küppers R. Goossens T, et al. Among authors: klein u. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2463-8. doi: 10.1073/pnas.95.5.2463. Proc Natl Acad Sci U S A. 1998. PMID: 9482908 Free PMC article.

9

Somatic hypermutation in normal and transformed human B cells.

Klein U, Goossens T, Fischer M, Kanzler H, Braeuninger A, Rajewsky K, Küppers R. Klein U, et al. Immunol Rev. 1998 Apr;162:261-80. doi: 10.1111/j.1600-065x.1998.tb01447.x. Immunol Rev. 1998. PMID: 9602370 Review.

10

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells.

Klein U, Rajewsky K, Küppers R. Klein U, et al. J Exp Med. 1998 Nov 2;188(9):1679-89. doi: 10.1084/jem.188.9.1679. J Exp Med. 1998. PMID: 9802980 Free PMC article.

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