van Breemen RB - Search Results

1

The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.

Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL. Chen Y, et al. Among authors: van breemen rb. Chem Res Toxicol. 1998 Sep;11(9):1105-11. doi: 10.1021/tx980083l. Chem Res Toxicol. 1998. PMID: 9760286

2

Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.

Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, van Breemen RB, Bolton JL. Shen L, et al. Among authors: van breemen rb. Carcinogenesis. 1997 May;18(5):1093-101. doi: 10.1093/carcin/18.5.1093. Carcinogenesis. 1997. PMID: 9163701

3

Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.

van Breemen RB, Huang CR, Nikolic D, Woodbury CP, Zhao YZ, Venton DL. van Breemen RB, et al. Anal Chem. 1997 Jun 1;69(11):2159-64. doi: 10.1021/ac970132j. Anal Chem. 1997. PMID: 9183179

4

The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells.

Bolton JL, Pisha E, Shen L, Krol ES, Iverson SL, Huang Z, van Breemen RB, Pezzuto JM. Bolton JL, et al. Among authors: van breemen rb. Chem Biol Interact. 1997 Sep 12;106(2):133-48. doi: 10.1016/s0009-2797(97)00066-5. Chem Biol Interact. 1997. PMID: 9366899

5

Screening solution-phase combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry.

Zhao YZ, van Breemen RB, Nikolic D, Huang CR, Woodbury CP, Schilling A, Venton DL. Zhao YZ, et al. Among authors: van breemen rb. J Med Chem. 1997 Dec 5;40(25):4006-12. doi: 10.1021/jm960729b. J Med Chem. 1997. PMID: 9406591

6

Metabolic screening using on-line ultrafiltration mass spectrometry.

van Breemen RB, Nikolic D, Bolton JL. van Breemen RB, et al. Drug Metab Dispos. 1998 Feb;26(2):85-90. Drug Metab Dispos. 1998. PMID: 9456292

7

Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.

van Breemen RB, Nikolic D, Xu X, Xiong Y, van Lieshout M, West CE, Schilling AB. van Breemen RB, et al. Among authors: van lieshout m. J Chromatogr A. 1998 Jan 23;794(1-2):245-51. doi: 10.1016/s0021-9673(97)01138-2. J Chromatogr A. 1998. PMID: 9491562

8

Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical.

Shen L, Qiu S, Chen Y, Zhang F, van Breemen RB, Nikolic D, Bolton JL. Shen L, et al. Among authors: van breemen rb. Chem Res Toxicol. 1998 Feb;11(2):94-101. doi: 10.1021/tx970181r. Chem Res Toxicol. 1998. PMID: 9511900

9

Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.

Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL. Chang M, et al. Among authors: van breemen rb. Chem Res Toxicol. 1998 Jul;11(7):758-65. doi: 10.1021/tx9702190. Chem Res Toxicol. 1998. PMID: 9671538

10

The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.

Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL. Zhang F, et al. Among authors: van breemen rb. Chem Res Toxicol. 1999 Feb;12(2):204-13. doi: 10.1021/tx980217v. Chem Res Toxicol. 1999. PMID: 10027800

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