Chen G - Search Results

1

Antibody affinity maturation using bacterial surface display.

Daugherty PS, Chen G, Olsen MJ, Iverson BL, Georgiou G. Daugherty PS, et al. Among authors: chen g. Protein Eng. 1998 Sep;11(9):825-32. doi: 10.1093/protein/11.9.825. Protein Eng. 1998. PMID: 9796833

2

A quantitative immunoassay utilizing Escherichia coli cells possessing surface-expressed single chain Fv molecules.

Chen G, Cloud J, Georgiou G, Iverson BL. Chen G, et al. Biotechnol Prog. 1996 Jul-Aug;12(4):572-4. doi: 10.1021/bp960041s. Biotechnol Prog. 1996. PMID: 8987483

3

In vitro scanning saturation mutagenesis of all the specificity determining residues in an antibody binding site.

Chen G, Dubrawsky I, Mendez P, Georgiou G, Iverson BL. Chen G, et al. Protein Eng. 1999 Apr;12(4):349-56. doi: 10.1093/protein/12.4.349. Protein Eng. 1999. PMID: 10325406

The studies were conducted on a variant of the 26-10 antidigoxin single chain Fv (scFv) using in vitro scanning saturation mutagenesis, a new process that allows the high throughput production and characterization of antibody mutants [Burks,E.A., Chen,G., Georgiou, …

The studies were conducted on a variant of the 26-10 antidigoxin single chain Fv (scFv) using in vitro scanning saturation mutagenesis, a ne …

4

Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies.

Daugherty PS, Chen G, Iverson BL, Georgiou G. Daugherty PS, et al. Among authors: chen g. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2029-34. doi: 10.1073/pnas.030527597. Proc Natl Acad Sci U S A. 2000. PMID: 10688877 Free PMC article.

5

Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones.

Levy R, Weiss R, Chen G, Iverson BL, Georgiou G. Levy R, et al. Among authors: chen g. Protein Expr Purif. 2001 Nov;23(2):338-47. doi: 10.1006/prep.2001.1520. Protein Expr Purif. 2001. PMID: 11676610

6

Isolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS).

Chen G, Hayhurst A, Thomas JG, Harvey BR, Iverson BL, Georgiou G. Chen G, et al. Nat Biotechnol. 2001 Jun;19(6):537-42. doi: 10.1038/89281. Nat Biotechnol. 2001. PMID: 11385457

7

In vitro scanning-saturation mutagenesis.

Maynard JA, Chen G, Georgiou G, Iverson BL. Maynard JA, et al. Among authors: chen g. Methods Mol Biol. 2002;182:149-63. doi: 10.1385/1-59259-194-9:149. Methods Mol Biol. 2002. PMID: 11768962 No abstract available.

8

In vitro scanning saturation mutagenesis of an antibody binding pocket.

Burks EA, Chen G, Georgiou G, Iverson BL. Burks EA, et al. Among authors: chen g. Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):412-7. doi: 10.1073/pnas.94.2.412. Proc Natl Acad Sci U S A. 1997. PMID: 9012796 Free PMC article.

9

Liver microsome and flavin-containing monooxygenase catalyzed oxidation of organic selenium compounds.

Chen GP, Ziegler DM. Chen GP, et al. Arch Biochem Biophys. 1994 Aug 1;312(2):566-72. doi: 10.1006/abbi.1994.1346. Arch Biochem Biophys. 1994. PMID: 8037472

10

Flavoenzymes inhibited by indomethacin.

Chen GP, Raybuck S, Ziegler DM. Chen GP, et al. Drug Metabol Drug Interact. 1994;11(2):153-60. doi: 10.1515/dmdi.1994.11.2.153. Drug Metabol Drug Interact. 1994. PMID: 12369598

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