Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.
Horton JD, Shimomura I, Ikemoto S, Bashmakov Y, Hammer RE.
Horton JD, et al. Among authors: bashmakov y.
J Biol Chem. 2003 Sep 19;278(38):36652-60. doi: 10.1074/jbc.M306540200. Epub 2003 Jul 10.
J Biol Chem. 2003.
PMID: 12855691
Free article.
Overexpression of the alternative SREBP-1 isoform, nSREBP-1c, in adipose tissue inhibits adipocyte differentiation; as a result, the transgenic nSREBP-1c mice develop a syndrome resembling human lipodystrophy, which includes a loss of peripheral white adipose tissue, diabetes, an …
Overexpression of the alternative SREBP-1 isoform, nSREBP-1c, in adipose tissue inhibits adipocyte differentiation; as a result, the transge …