Yoshimura T - Search Results

1

Peptidyl human heart chymase inhibitors. 2. Discovery of highly selective difluoromethylene ketone derivatives with Glu at P3 site.

Eda M, Ashimori A, Akahoshi F, Yoshimura T, Inoue Y, Fukaya C, Nakajima M, Fukuyama H, Imada T, Takai S, Shiota N, Miyazaki M, Nakamura N. Eda M, et al. Among authors: yoshimura t. Bioorg Med Chem Lett. 1998 Apr 21;8(8):919-24. doi: 10.1016/s0960-894x(98)00132-2. Bioorg Med Chem Lett. 1998. PMID: 9871512

2

Peptidyl human heart chymase inhibitors. 1. Synthesis and inhibitory activity of difluoromethylene ketone derivatives bearing P' binding subsites.

Eda M, Ashimori A, Akahoshi F, Yoshimura T, Inoue Y, Fukaya C, Nakajima M, Fukuyama H, Imada T, Takai S, Shiota N, Miyazaki M, Nakamura N. Eda M, et al. Among authors: yoshimura t. Bioorg Med Chem Lett. 1998 Apr 21;8(8):913-8. doi: 10.1016/s0960-894x(98)00131-0. Bioorg Med Chem Lett. 1998. PMID: 9871511

3

Non-peptidic inhibitors of human chymase. Synthesis, structure-activity relationships, and pharmacokinetic profiles of a series of 5-amino-6-oxo-1,6-dihydropyrimidine-containing trifluoromethyl ketones.

Akahoshi F, Ashimori A, Yoshimura T, Imada T, Nakajima M, Mitsutomi N, Kuwahara S, Ohtsuka T, Fukaya C, Miyazaki M, Nakamura N. Akahoshi F, et al. Among authors: yoshimura t. Bioorg Med Chem. 2001 Feb;9(2):301-15. doi: 10.1016/s0968-0896(00)00244-3. Bioorg Med Chem. 2001. PMID: 11249123

4

Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic alpha-keto heterocycles as novel inhibitors of human chymase.

Akahoshi F, Ashimori A, Sakashita H, Yoshimura T, Imada T, Nakajima M, Mitsutomi N, Kuwahara S, Ohtsuka T, Fukaya C, Miyazaki M, Nakamura N. Akahoshi F, et al. Among authors: yoshimura t. J Med Chem. 2001 Apr 12;44(8):1286-96. doi: 10.1021/jm000496v. J Med Chem. 2001. PMID: 11312927

5

Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic difluoromethylene ketones as novel inhibitors of human chymase.

Akahoshi F, Ashimori A, Sakashita H, Yoshimura T, Eda M, Imada T, Nakajima M, Mitsutomi N, Kuwahara S, Ohtsuka T, Fukaya C, Miyazaki M, Nakamura N. Akahoshi F, et al. Among authors: yoshimura t. J Med Chem. 2001 Apr 12;44(8):1297-304. doi: 10.1021/jm000497n. J Med Chem. 2001. PMID: 11312928

6

Diastereoselective two-directional synthesis and cation transport ability of the central tristetrahydrofuranyl unit of meso polyether glabrescol as naturally occurring podand.

Morimoto Y, Iwai T, Yoshimura T, Kinoshita T. Morimoto Y, et al. Among authors: yoshimura t. Bioorg Med Chem Lett. 1998 Aug 4;8(15):2005-10. doi: 10.1016/s0960-894x(98)00347-3. Bioorg Med Chem Lett. 1998. PMID: 9873476

7

Syntheses of novel antitumor dihydroxanthone derivatives with inhibitory activity against DNA topoisomerase II.

Sato S, Suga Y, Yoshimura T, Nakagawa R, Tsuji T, Umemura K, Andoh T. Sato S, et al. Among authors: yoshimura t. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2653-6. doi: 10.1016/s0960-894x(99)00440-0. Bioorg Med Chem Lett. 1999. PMID: 10509910

8

Anchoring and bola cationic amphiphiles for nucleotide delivery. Effects of orientation and extension of hydrophobic regions.

Yoshimura T, Hasegawa S, Hirashima N, Nakanishi M, Ohwada T. Yoshimura T, et al. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2897-901. doi: 10.1016/s0960-894x(01)00563-7. Bioorg Med Chem Lett. 2001. PMID: 11677122

9

F390B and C, new antitumor dihydroxanthone derivatives isolated from Penicillium sp.

Sato S, Nakagawa R, Fudo R, Fukuda Y, Yoshimura T, Kaida K, Ando T, Kameyama T, Tsuji T. Sato S, et al. Among authors: yoshimura t. J Antibiot (Tokyo). 1997 Jul;50(7):614-6. doi: 10.7164/antibiotics.50.614. J Antibiot (Tokyo). 1997. PMID: 9711252 Free article. No abstract available.

10

cDNA cloning of mouse ferredoxin reductase from kidney.

Itoh S, Iemura O, Yamada E, Yoshimura T, Tsujikawa K, Kohama Y, Mimura T. Itoh S, et al. Among authors: yoshimura t. Biochim Biophys Acta. 1995 Nov 7;1264(2):159-62. doi: 10.1016/0167-4781(95)00172-d. Biochim Biophys Acta. 1995. PMID: 7495857

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