Iimura S - Search Results

1

Synthesis and cytotoxic activity of novel 10-alkylated docetaxel analogs.

Nakayama K, Terasawa H, Mitsui I, Ohsuki S, Uoto K, Iimura S, Soga T. Nakayama K, et al. Among authors: iimura s. Bioorg Med Chem Lett. 1998 Mar 3;8(5):427-32. doi: 10.1016/s0960-894x(98)00040-7. Bioorg Med Chem Lett. 1998. PMID: 9871592

2

New highly active taxoids from 9 beta-dihydrobaccatin-9,10-acetals.

Ishiyama T, Iimura S, Ohsuki S, Uoto K, Terasawa H, Soga T. Ishiyama T, et al. Among authors: iimura s. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1083-6. doi: 10.1016/s0960-894x(02)00069-0. Bioorg Med Chem Lett. 2002. PMID: 11909723

3

New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 2.

Ishiyama T, Iimura S, Yoshino T, Chiba J, Uoto K, Terasawa H, Soga T. Ishiyama T, et al. Among authors: iimura s. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2815-9. doi: 10.1016/s0960-894x(02)00628-5. Bioorg Med Chem Lett. 2002. PMID: 12270153

4

Synthesis and structure-activity relationships of novel 2',2'-difluoro analogues of docetaxel.

Uoto K, Ohsuki S, Takenoshita H, Ishiyama T, Iimura S, Hirota Y, Mitsui I, Terasawa H, Soga T. Uoto K, et al. Among authors: iimura s. Chem Pharm Bull (Tokyo). 1997 Nov;45(11):1793-804. doi: 10.1248/cpb.45.1793. Chem Pharm Bull (Tokyo). 1997. PMID: 9396156

5

Orally active docetaxel analogue: synthesis of 10-deoxy-10-C-morpholinoethyl docetaxel analogues.

Iimura S, Uoto K, Ohsuki S, Chiba J, Yoshino T, Iwahana M, Jimbo T, Terasawa H, Soga T. Iimura S, et al. Bioorg Med Chem Lett. 2001 Feb 12;11(3):407-10. doi: 10.1016/s0960-894x(00)00682-x. Bioorg Med Chem Lett. 2001. PMID: 11212122

6

Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity.

Taniguchi T, Inagaki H, Baba D, Yasumatsu I, Toyota A, Kaneta Y, Kiga M, Iimura S, Odagiri T, Shibata Y, Ueda K, Seo M, Shimizu H, Imaoka T, Nakayama K. Taniguchi T, et al. Among authors: iimura s. ACS Med Chem Lett. 2019 Mar 15;10(5):737-742. doi: 10.1021/acsmedchemlett.8b00631. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31097992 Free PMC article.

7

A novel and potent VLA-4 antagonist based on trans-4-substituted cyclohexanecarboxylic acid.

Muro F, Iimura S, Yoneda Y, Chiba J, Watanabe T, Setoguchi M, Takayama G, Yokoyama M, Takashi T, Nakayama A, Machinaga N. Muro F, et al. Among authors: iimura s. Bioorg Med Chem. 2009 Feb 1;17(3):1232-43. doi: 10.1016/j.bmc.2008.12.026. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19124247

8

Synthesis and biological evaluation of benzoic acid derivatives as potent, orally active VLA-4 antagonists.

Chiba J, Iimura S, Yoneda Y, Watanabe T, Muro F, Tsubokawa M, Iigou Y, Satoh A, Takayama G, Yokoyama M, Takashi T, Nakayama A, Machinaga N. Chiba J, et al. Among authors: iimura s. Bioorg Med Chem. 2007 Feb 15;15(4):1679-93. doi: 10.1016/j.bmc.2006.12.006. Epub 2006 Dec 9. Bioorg Med Chem. 2007. PMID: 17194595

9

Identification of 4-[1-[3-chloro-4-[N'-(5-fluoro-2-methylphenyl)ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]benzoic acid as a potent, orally active VLA-4 antagonist.

Muro F, Iimura S, Yoneda Y, Chiba J, Watanabe T, Setoguchi M, Iigou Y, Takayama G, Yokoyama M, Takashi T, Nakayama A, Machinaga N. Muro F, et al. Among authors: iimura s. Bioorg Med Chem. 2008 Dec 1;16(23):9991-10000. doi: 10.1016/j.bmc.2008.10.020. Epub 2008 Oct 12. Bioorg Med Chem. 2008. PMID: 18952443

10

Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist.

Muro F, Iimura S, Sugimoto Y, Yoneda Y, Chiba J, Watanabe T, Setoguchi M, Iigou Y, Matsumoto K, Satoh A, Takayama G, Taira T, Yokoyama M, Takashi T, Nakayama A, Machinaga N. Muro F, et al. Among authors: iimura s. J Med Chem. 2009 Dec 24;52(24):7974-92. doi: 10.1021/jm901154c. J Med Chem. 2009. PMID: 19891440

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