Afford SC - Search Results

1

CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection.

Afford SC, Randhawa S, Eliopoulos AG, Hubscher SG, Young LS, Adams DH. Afford SC, et al. J Exp Med. 1999 Jan 18;189(2):441-6. doi: 10.1084/jem.189.2.441. J Exp Med. 1999. PMID: 9892626 Free PMC article.

2

Differential induction of nuclear factor-kappaB and activator protein-1 activity after CD40 ligation is associated with primary human hepatocyte apoptosis or intrahepatic endothelial cell proliferation.

Ahmed-Choudhury J, Russell CL, Randhawa S, Young LS, Adams DH, Afford SC. Ahmed-Choudhury J, et al. Among authors: afford sc. Mol Biol Cell. 2003 Apr;14(4):1334-45. doi: 10.1091/mbc.e02-07-0378. Mol Biol Cell. 2003. PMID: 12686591 Free PMC article.

3

Effector mechanisms of nonsuppurative destructive cholangitis in graft-versus-host disease and allograft rejection.

Adams DH, Afford SC. Adams DH, et al. Among authors: afford sc. Semin Liver Dis. 2005 Aug;25(3):281-97. doi: 10.1055/s-2005-916320. Semin Liver Dis. 2005. PMID: 16143944 Review.

4

Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.

Humphreys EH, Williams KT, Adams DH, Afford SC. Humphreys EH, et al. Among authors: afford sc. PLoS One. 2010 Nov 17;5(11):e14037. doi: 10.1371/journal.pone.0014037. PLoS One. 2010. PMID: 21103345 Free PMC article.

5

Apoptosis in the human liver during allograft rejection and end-stage liver disease.

Afford SC, Hubscher S, Strain AJ, Adams DH, Neuberger JM. Afford SC, et al. J Pathol. 1995 Aug;176(4):373-80. doi: 10.1002/path.1711760408. J Pathol. 1995. PMID: 7562252

6

Fas/Fas ligand interaction in human colorectal hepatic metastases: A mechanism of hepatocyte destruction to facilitate local tumor invasion.

Yoong KF, Afford SC, Randhawa S, Hubscher SG, Adams DH. Yoong KF, et al. Among authors: afford sc. Am J Pathol. 1999 Mar;154(3):693-703. doi: 10.1016/S0002-9440(10)65316-3. Am J Pathol. 1999. PMID: 10079247 Free PMC article.

7

CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily.

Eliopoulos AG, Davies C, Knox PG, Gallagher NJ, Afford SC, Adams DH, Young LS. Eliopoulos AG, et al. Among authors: afford sc. Mol Cell Biol. 2000 Aug;20(15):5503-15. doi: 10.1128/MCB.20.15.5503-5515.2000. Mol Cell Biol. 2000. PMID: 10891490 Free PMC article.

8

CD40 activation-induced, Fas-dependent apoptosis and NF-kappaB/AP-1 signaling in human intrahepatic biliary epithelial cells.

Afford SC, Ahmed-Choudhury J, Randhawa S, Russell C, Youster J, Crosby HA, Eliopoulos A, Hubscher SG, Young LS, Adams DH. Afford SC, et al. FASEB J. 2001 Nov;15(13):2345-54. doi: 10.1096/fj.01-0088com. FASEB J. 2001. PMID: 11689460

9

Apoptosis.

Afford S, Randhawa S. Afford S, et al. Mol Pathol. 2000 Apr;53(2):55-63. doi: 10.1136/mp.53.2.55. Mol Pathol. 2000. PMID: 10889903 Free PMC article. Review.

10

Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosis.

Chen YY, Jeffery HC, Hunter S, Bhogal R, Birtwistle J, Braitch MK, Roberts S, Ming M, Hannah J, Thomas C, Adali G, Hübscher SG, Syn WK, Afford S, Lalor PF, Adams DH, Oo YH. Chen YY, et al. Hepatology. 2016 Jul;64(1):138-50. doi: 10.1002/hep.28517. Epub 2016 Apr 15. Hepatology. 2016. PMID: 26928938 Free PMC article.

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