Cytogenetic mapping of DGAT1, PPARA, ADIPOR1 and CREB genes in the pig

Izabela Szczerbal; Li Lin; Monika Stachowiak; Agata Chmurzynska; Mariusz Mackowski; Andreas Winter; Krzysztof Flisikowski; Ruedi Fries; Marek Switonski

doi:10.1007/BF03194660

Cytogenetic mapping of DGAT1, PPARA, ADIPOR1 and CREB genes in the pig

J Appl Genet. 2007;48(1):73-6. doi: 10.1007/BF03194660.

Authors

Izabela Szczerbal¹, Li Lin, Monika Stachowiak, Agata Chmurzynska, Mariusz Mackowski, Andreas Winter, Krzysztof Flisikowski, Ruedi Fries, Marek Switonski

Affiliation

¹ Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznań, Poland.

PMID: 17272864
DOI: 10.1007/BF03194660

Abstract

In the present study we show FISH localization of 4 porcine BAC clones harbouring potential candidate genes for fatness traits: DGAT1 (SSC4p15), PPARA (SSC5p15), ADIPOR1 (SSC10p13) and CREB (SSC15q24). Until now the CREB and ADIPOR1 genes are considered to be monomorphic, DGAT1 is highly polymorphic, while for the PPARA gene only 1 SNP was identified. Assignment of the studied genes in relation to QTL chromosome regions for meat quality in pig chromosomes SSC4, SSC5, SSC10 and SSC15 is discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adiponectin / metabolism
Animals
Base Sequence
Chromosome Mapping / veterinary
Chromosomes, Artificial, Bacterial / genetics
Cyclic AMP Response Element-Binding Protein / genetics*
Cytogenetics
DNA Primers / genetics
Diacylglycerol O-Acyltransferase / genetics*
In Situ Hybridization, Fluorescence
PPAR alpha / genetics*
Receptors, Cell Surface / genetics
Sus scrofa / genetics*

Substances

Adiponectin
Cyclic AMP Response Element-Binding Protein
DNA Primers
PPAR alpha
Receptors, Cell Surface
Diacylglycerol O-Acyltransferase