10-0230/AICR_/Worldwide Cancer Research/United Kingdom[Grants and Funding] - Search Results

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2025	0

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Bax dimerizes via a symmetric BH3:groove interface during apoptosis.

Dewson G, Ma S, Frederick P, Hockings C, Tan I, Kratina T, Kluck RM. Dewson G, et al. Cell Death Differ. 2012 Apr;19(4):661-70. doi: 10.1038/cdd.2011.138. Epub 2011 Oct 21. Cell Death Differ. 2012. PMID: 22015607 Free PMC article.

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.

Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM. Hockings C, et al. Cell Death Dis. 2015 Apr 23;6(4):e1735. doi: 10.1038/cddis.2015.105. Cell Death Dis. 2015. PMID: 25906158 Free PMC article.

Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.

Ferrer PE, Frederick P, Gulbis JM, Dewson G, Kluck RM. Ferrer PE, et al. PLoS One. 2012;7(3):e31510. doi: 10.1371/journal.pone.0031510. Epub 2012 Mar 19. PLoS One. 2012. PMID: 22442658 Free PMC article.

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