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Pancreatic cancer screening is effective in individuals at risk with predisposing germline gene variants, but not in gene variant-negative familial pancreatic cancer families.
Maurer E, Lehman B, Matthäi E, Denzer U, Figiel J, Jesinghaus M, Slater EP, Stefenelli U, Gress TM, Bartsch DK. Maurer E, et al. United European Gastroenterol J. 2024 Nov;12(9):1211-1221. doi: 10.1002/ueg2.12631. Epub 2024 Jul 19. United European Gastroenterol J. 2024. PMID: 39031472 Free PMC article.
The Combination of MiRNA-196b, LCN2, and TIMP1 is a Potential Set of Circulating Biomarkers for Screening Individuals at Risk for Familial Pancreatic Cancer.
Bartsch DK, Gercke N, Strauch K, Wieboldt R, Matthäi E, Wagner V, Rospleszcz S, Schäfer A, Franke FS, Mintziras I, Bauer C, Grote T, Figiel J, Di Fazio P, Burchert A, Reinartz S, Pogge von Strandmann E, Klöppel G, Slater EP. Bartsch DK, et al. J Clin Med. 2018 Sep 20;7(10):295. doi: 10.3390/jcm7100295. J Clin Med. 2018. PMID: 30241369 Free PMC article.