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Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis.
Whitehead A, Krause FN, Moran A, MacCannell ADV, Scragg JL, McNally BD, Boateng E, Murfitt SA, Virtue S, Wright J, Garnham J, Davies GR, Dodgson J, Schneider JE, Murray AJ, Church C, Vidal-Puig A, Witte KK, Griffin JL, Roberts LD. Whitehead A, et al. Nat Commun. 2021 Mar 26;12(1):1905. doi: 10.1038/s41467-021-22272-3. Nat Commun. 2021. PMID: 33772024 Free PMC article.
Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.
Haywood NJ, Luk C, Bridge KI, Drozd M, Makava N, Skromna A, Maccannell A, Ozber CH, Warmke N, Wilkinson CG, Watt NT, Koch-Paszkowski J, Teh I, Boyle JH, Smart S, Schneider JE, Yuldasheva NY, Roberts LD, Beech DJ, Sukumar P, Wheatcroft SB, Cubbon RM, Kearney MT. Haywood NJ, et al. EMBO Rep. 2021 May 5;22(5):e50767. doi: 10.15252/embr.202050767. Epub 2021 May 2. EMBO Rep. 2021. PMID: 33934497 Free PMC article.