An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair

Affiliations

• ¹ Duke Regeneration Center, Duke University, Durham, NC, USA; Department of Cell Biology, Duke University Medical School, Durham, NC, USA.
• ² Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
• ³ Department of Cell Biology, Duke University Medical School, Durham, NC, USA; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
• ⁴ Duke Regeneration Center, Duke University, Durham, NC, USA; Department of Cell Biology, Duke University Medical School, Durham, NC, USA; Department of Surgery, Duke University School of Medicine, Durham, NC, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
• ⁵ Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
• ⁶ Department of Biomedical Engineering, Duke University, Durham, NC, USA; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
• ⁷ Department of Biomedical Engineering, Duke University, Durham, NC, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
• ⁸ Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.
• ⁹ Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.
• ¹⁰ Department of Medicine, Duke University Medical Center, Durham, NC, USA.
• ¹¹ Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, NC, USA.
• ¹² Duke Regeneration Center, Duke University, Durham, NC, USA.
• ¹³ Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
• ¹⁴ Department of Biological Chemistry and Pharmacology, Ohio State University, Columbus, OH, USA.
• ¹⁵ Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA; Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
• ¹⁶ Duke Regeneration Center, Duke University, Durham, NC, USA; Department of Biomedical Engineering, Duke University, Durham, NC, USA; Department of Surgery, Duke University School of Medicine, Durham, NC, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
• ¹⁷ Duke Regeneration Center, Duke University, Durham, NC, USA; Department of Cell Biology, Duke University Medical School, Durham, NC, USA; Department of Biomedical Engineering, Duke University, Durham, NC, USA; Department of Surgery, Duke University School of Medicine, Durham, NC, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA; Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
• ¹⁸ Department of Biomedical Engineering, Duke University, Durham, NC, USA.
• ¹⁹ Duke Regeneration Center, Duke University, Durham, NC, USA; Department of Cell Biology, Duke University Medical School, Durham, NC, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA. Electronic address: [email protected].