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Intercellular Molecular Crosstalk Networks within Invasive and Immunosuppressive Tumor Microenvironment Subtypes Associated with Clinical Outcomes in Four Cancer Types.
Wei J, Yu W, Wu L, Chen Z, Huang G, Hu M, Du H. Wei J, et al. Biomedicines. 2023 Nov 14;11(11):3057. doi: 10.3390/biomedicines11113057. Biomedicines. 2023. PMID: 38002057 Free PMC article.
Overall, our study revealed the heterogeneity within the TME, highlighting the potential pro-invasion and pro-immunosuppressive functions and cellular infiltration characteristics of specific subTMEs, and also identified the key cellular and molecular interactions that mig …
Overall, our study revealed the heterogeneity within the TME, highlighting the potential pro-invasion and pro-immunosuppressive functions an …
Characterization of Glycolysis-Associated Molecules in the Tumor Microenvironment Revealed by Pan-Cancer Tissues and Lung Cancer Single Cell Data.
Wei J, Huang K, Chen Z, Hu M, Bai Y, Lin S, Du H. Wei J, et al. Cancers (Basel). 2020 Jul 4;12(7):1788. doi: 10.3390/cancers12071788. Cancers (Basel). 2020. PMID: 32635458 Free PMC article.
Glycolysis signature was strongly correlated with hypoxia signature in all 25 cancer tissues (r > 0.7) and cancer single cells (r > 0.8). In addition, HSPA8 and P4HA1 were screened out as the potential modulating factors to glycolysis as their expression were …
Glycolysis signature was strongly correlated with hypoxia signature in all 25 cancer tissues (r > 0.7) and cancer single cells ( …
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