SREBP1c-Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells.
Xin W, Zhou J, Peng Y, Gong S, Liao W, Wang Y, Huang X, Mao Y, Yao M, Qin S, Xiong J, Li Y, Lan Q, Huang Y, Zhao J.
Xin W, et al.
Adv Sci (Weinh). 2024 Dec 16:e2412233. doi: 10.1002/advs.202412233. Online ahead of print.
Adv Sci (Weinh). 2024.
PMID: 39680752
Accumulating studies suggest mitochondrial dysfunction as the typical characteristics and key process of AKI, but the underlying mechanism remains elusive. The YME1-like 1 (YME1L1) ATPase, an inner mitochondrial membrane protein, is screened and identified to be downregula …
Accumulating studies suggest mitochondrial dysfunction as the typical characteristics and key process of AKI, but the underlying mech …