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2015 5
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39 results

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Page 1
The NALCN channel regulates metastasis and nonmalignant cell dissemination.
Rahrmann EP, Shorthouse D, Jassim A, Hu LP, Ortiz M, Mahler-Araujo B, Vogel P, Paez-Ribes M, Fatemi A, Hannon GJ, Iyer R, Blundon JA, Lourenço FC, Kay J, Nazarian RM, Hall BA, Zakharenko SS, Winton DJ, Zhu L, Gilbertson RJ. Rahrmann EP, et al. Nat Genet. 2022 Dec;54(12):1827-1838. doi: 10.1038/s41588-022-01182-0. Epub 2022 Sep 29. Nat Genet. 2022. PMID: 36175792 Free PMC article.
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Samir P, Kesavardhana S, Patmore DM, Gingras S, Malireddi RKS, Karki R, Guy CS, Briard B, Place DE, Bhattacharya A, Sharma BR, Nourse A, King SV, Pitre A, Burton AR, Pelletier S, Gilbertson RJ, Kanneganti TD. Samir P, et al. Nature. 2019 Sep;573(7775):590-594. doi: 10.1038/s41586-019-1551-2. Epub 2019 Sep 11. Nature. 2019. PMID: 31511697 Free PMC article.
Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.
Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K, Ogurek S, Liu X, Rao R, Xing R, Wu LMN, Cui S, Xu L, Lin Y, Ma W, Tian S, Xie Q, Zhang L, Xin M, Wang X, Yue F, Zheng H, Liu Y, Stevenson CB, de Blank P, Perentesis JP, Gilbertson RJ, Li H, Ma J, Zhou W, Taylor MD, Lu QR. Luo Z, et al. Nature. 2022 Dec;612(7941):787-794. doi: 10.1038/s41586-022-05487-2. Epub 2022 Nov 30. Nature. 2022. PMID: 36450980
Serial assessment of measurable residual disease in medulloblastoma liquid biopsies.
Liu APY, Smith KS, Kumar R, Paul L, Bihannic L, Lin T, Maass KK, Pajtler KW, Chintagumpala M, Su JM, Bouffet E, Fisher MJ, Gururangan S, Cohn R, Hassall T, Hansford JR, Klimo P Jr, Boop FA, Stewart CF, Harreld JH, Merchant TE, Tatevossian RG, Neale G, Lear M, Klco JM, Orr BA, Ellison DW, Gilbertson RJ, Onar-Thomas A, Gajjar A, Robinson GW, Northcott PA. Liu APY, et al. Cancer Cell. 2021 Nov 8;39(11):1519-1530.e4. doi: 10.1016/j.ccell.2021.09.012. Epub 2021 Oct 21. Cancer Cell. 2021. PMID: 34678152 Free PMC article.
Multiomic Medulloblastomas.
Rahmann EP, Gilbertson RJ. Rahmann EP, et al. Cancer Cell. 2018 Sep 10;34(3):351-353. doi: 10.1016/j.ccell.2018.08.010. Cancer Cell. 2018. PMID: 30205039 Free article.
Cancer Treatment in the Genomic Era.
Doherty GJ, Petruzzelli M, Beddowes E, Ahmad SS, Caldas C, Gilbertson RJ. Doherty GJ, et al. Annu Rev Biochem. 2019 Jun 20;88:247-280. doi: 10.1146/annurev-biochem-062917-011840. Epub 2019 Mar 22. Annu Rev Biochem. 2019. PMID: 30901264 Review.
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM. Waszak SM, et al. Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9. Lancet Oncol. 2018. PMID: 29753700 Free PMC article.
Challenges to curing primary brain tumours.
Aldape K, Brindle KM, Chesler L, Chopra R, Gajjar A, Gilbert MR, Gottardo N, Gutmann DH, Hargrave D, Holland EC, Jones DTW, Joyce JA, Kearns P, Kieran MW, Mellinghoff IK, Merchant M, Pfister SM, Pollard SM, Ramaswamy V, Rich JN, Robinson GW, Rowitch DH, Sampson JH, Taylor MD, Workman P, Gilbertson RJ. Aldape K, et al. Nat Rev Clin Oncol. 2019 Aug;16(8):509-520. doi: 10.1038/s41571-019-0177-5. Nat Rev Clin Oncol. 2019. PMID: 30733593 Free PMC article. Review.
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
Arabzade A, Zhao Y, Varadharajan S, Chen HC, Jessa S, Rivas B, Stuckert AJ, Solis M, Kardian A, Tlais D, Golbourn BJ, Stanton AJ, Chan YS, Olson C, Karlin KL, Kong K, Kupp R, Hu B, Injac SG, Ngo M, Wang PR, De León LA, Sahm F, Kawauchi D, Pfister SM, Lin CY, Hodges HC, Singh I, Westbrook TF, Chintagumpala MM, Blaney SM, Parsons DW, Pajtler KW, Agnihotri S, Gilbertson RJ, Yi J, Jabado N, Kleinman CL, Bertrand KC, Deneen B, Mack SC. Arabzade A, et al. Cancer Discov. 2021 Sep;11(9):2200-2215. doi: 10.1158/2159-8290.CD-20-1066. Epub 2021 Mar 19. Cancer Discov. 2021. PMID: 33741710 Free PMC article.
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Panwalkar P, Tamrazi B, Dang D, Chung C, Sweha S, Natarajan SK, Pun M, Bayliss J, Ogrodzinski MP, Pratt D, Mullan B, Hawes D, Yang F, Lu C, Sabari BR, Achreja A, Heon J, Animasahun O, Cieslik M, Dunham C, Yip S, Hukin J, Phillips JJ, Bornhorst M, Griesinger AM, Donson AM, Foreman NK, Garton HJL, Heth J, Muraszko K, Nazarian J, Koschmann C, Jiang L, Filbin MG, Nagrath D, Kool M, Korshunov A, Pfister SM, Gilbertson RJ, Allis CD, Chinnaiyan AM, Lunt SY, Blüml S, Judkins AR, Venneti S. Panwalkar P, et al. Sci Transl Med. 2021 Oct 6;13(614):eabc0497. doi: 10.1126/scitranslmed.abc0497. Epub 2021 Oct 6. Sci Transl Med. 2021. PMID: 34613815 Free PMC article.
39 results