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Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
Griess K, Rieck M, Müller N, Karsai G, Hartwig S, Pelligra A, Hardt R, Schlegel C, Kuboth J, Uhlemeyer C, Trenkamp S, Jeruschke K, Weiss J, Peifer-Weiss L, Xu W, Cames S, Yi X, Cnop M, Beller M, Stark H, Kondadi AK, Reichert AS, Markgraf D, Wammers M, Häussinger D, Kuss O, Lehr S, Eizirik D, Lickert H, Lammert E, Roden M, Winter D, Al-Hasani H, Höglinger D, Hornemann T, Brüning JC, Belgardt BF. Griess K, et al. Nat Cell Biol. 2023 Jan;25(1):20-29. doi: 10.1038/s41556-022-01027-2. Epub 2022 Dec 21. Nat Cell Biol. 2023. PMID: 36543979 Free PMC article.
Extensive protein pyrophosphorylation revealed in human cell lines.
Morgan JAM, Singh A, Kurz L, Nadler-Holly M, Ruwolt M, Ganguli S, Sharma S, Penkert M, Krause E, Liu F, Bhandari R, Fiedler D. Morgan JAM, et al. Nat Chem Biol. 2024 Oct;20(10):1305-1316. doi: 10.1038/s41589-024-01613-5. Epub 2024 Apr 25. Nat Chem Biol. 2024. PMID: 38664588 Free PMC article.