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PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.
J Clin Invest. 2009 Dec;119(12):3774-86. doi: 10.1172/JCI39692. Epub 2009 Nov 9.
J Clin Invest. 2009.
PMID: 19907075
Free PMC article.
GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression.
Miller WP, Srinivasan S, Panoskaltsis-Mortari A, Singh K, Sen S, Hamby K, Deane T, Stempora L, Beus J, Turner A, Wheeler C, Anderson DC, Sharma P, Garcia A, Strobert E, Elder E, Crocker I, Crenshaw T, Penedo MC, Ward T, Song M, Horan J, Larsen CP, Blazar BR, Kean LS.
Miller WP, et al.
Blood. 2010 Dec 9;116(24):5403-18. doi: 10.1182/blood-2010-06-289272. Epub 2010 Sep 10.
Blood. 2010.
PMID: 20833977
Free PMC article.
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